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3R7B
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BU of 3r7b by Molmil
Caspase-2 bound to one copy of Ac-DVAD-CHO
分子名称: Caspase-2 subunit p12, Caspase-2 subunit p18, Peptide Inhibitor (ACE)DVAD-CHO
著者Tang, Y, Wells, J, Arkin, M.
登録日2011-03-22
公開日2011-07-27
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis.
J.Biol.Chem., 286, 2011
2CJX
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BU of 2cjx by Molmil
Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis
分子名称: CASPASE-3, PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE
著者Ganesan, R, Mittl, P.R.E, Jelakovic, S, Grutter, M.G.
登録日2006-04-09
公開日2006-06-27
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-Ray Structure Analysis
J.Mol.Biol., 359, 2006
2CNO
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BU of 2cno by Molmil
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
分子名称: Aza-peptide epoxide, Caspase-3
著者Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Powers, J.C, Grutter, M.G.
登録日2006-05-22
公開日2007-05-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors
Biochemistry, 45, 2006
2CDR
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BU of 2cdr by Molmil
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
分子名称: AZA-PEPTIDE EXPOXIDE, CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17
著者Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Powers, J.C, Gruetter, M.G.
登録日2006-01-27
公開日2007-03-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors.
Biochemistry, 45, 2006
2CNL
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BU of 2cnl by Molmil
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
分子名称: AZA-PEPTIDE EPOXIDE, CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17
著者Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Grutter, M.G, Powers, J.C.
登録日2006-05-22
公開日2007-05-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors
Biochemistry, 45, 2006
2CNN
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BU of 2cnn by Molmil
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
分子名称: AZA-PEPTIDE EXPOXIDE, Caspase-3
著者Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Powers, J.C, Grutter, M.G.
登録日2006-05-22
公開日2007-05-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors
Biochemistry, 45, 2006
2CNK
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BU of 2cnk by Molmil
Crystal structures of caspase-3 in complex with aza-peptide epoxide inhibitors.
分子名称: AZA-PEPTIDE EXPOXIDE, CASPASE-3 P12 SUBUNIT, CASPASE-3 P17 SUBUNIT
著者Ganesan, R, Jelakovic, S, Campbell, A.J, Li, Z.Z, Asgian, J.L, Powers, J.C, Grutter, M.G.
登録日2006-05-22
公開日2007-05-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Exploring the S4 and S1 Prime Subsite Specificities in Caspase-3 with Aza-Peptide Epoxide Inhibitors
Biochemistry, 45, 2006
2FP3
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BU of 2fp3 by Molmil
Crystal structure of the Drosophila initiator caspase Dronc
分子名称: Caspase Nc
著者Yan, N, Gu, L, Shi, Y.
登録日2006-01-15
公開日2006-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and activation mechanism of the Drosophila initiator caspase dronc
J.Biol.Chem., 281, 2006
2FQQ
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BU of 2fqq by Molmil
Crystal structure of human caspase-1 (Cys285->Ala, Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (2-mercapto-ethyl)-amide
分子名称: 1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE, Caspase-1
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-01-18
公開日2006-05-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A common allosteric site and mechanism in caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2CJY
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BU of 2cjy by Molmil
Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis
分子名称: CASPASE-3, PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE
著者Ganesan, R, Mittl, P.R.E, Jelakovic, S, Grutter, M.G.
登録日2006-04-09
公開日2006-06-27
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-Ray Structure Analysis
J.Mol.Biol., 359, 2006
2H4Y
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BU of 2h4y by Molmil
Crystal structure of human caspase-1 (Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-05-25
公開日2008-03-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An allosteric circuit in caspase-1.
J.Mol.Biol., 381, 2008
2H51
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BU of 2h51 by Molmil
Crystal structure of human caspase-1 (Glu390->Asp and Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-05-25
公開日2008-03-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An allosteric circuit in caspase-1.
J.Mol.Biol., 381, 2008
2H5J
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BU of 2h5j by Molmil
Crystal strusture of caspase-3 with inhibitor Ac-DMQD-Cho
分子名称: Ac-DMQD-Cho, caspase-3, p12 subunit, ...
著者Fang, B, Boross, P.I, Tozser, J, Weber, I.T.
登録日2006-05-26
公開日2006-09-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition
J.Mol.Biol., 360, 2006
2DKO
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BU of 2dko by Molmil
Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis
分子名称: Caspase-3, PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE
著者Mittl, P.R.E, Ganesan, R, Jelakovic, S, Grutter, M.G.
登録日2006-04-12
公開日2006-07-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-ray Structure Analysis
J.Mol.Biol., 359, 2006
2HBQ
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BU of 2hbq by Molmil
Crystal structure of wildtype human caspase-1 in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-06-14
公開日2006-06-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Common Allosteric Site and Mechanism in Caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2H5I
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BU of 2h5i by Molmil
Crystal structure of caspase-3 with inhibitor Ac-DEVD-Cho
分子名称: Ac-DEV(ASJ), caspase-3, p12 subunit, ...
著者Fang, B, Boross, P.I, Tozser, J, Weber, I.T.
登録日2006-05-26
公開日2006-09-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition
J.Mol.Biol., 360, 2006
2H48
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BU of 2h48 by Molmil
Crystal structure of human caspase-1 (Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase 1, isoform gamma, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-05-23
公開日2006-06-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A common allosteric site and mechanism in caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2H54
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BU of 2h54 by Molmil
Crystal structure of human caspase-1 (Thr388->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-05-25
公開日2008-03-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An allosteric circuit in caspase-1.
J.Mol.Biol., 381, 2008
2H4W
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BU of 2h4w by Molmil
Crystal structure of human caspase-1 (Glu390->Asp) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-05-25
公開日2008-03-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An allosteric circuit in caspase-1.
J.Mol.Biol., 381, 2008
2HBR
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BU of 2hbr by Molmil
Crystal structure of human caspase-1 (Arg286->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-06-14
公開日2006-06-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Common Allosteric Site and Mechanism in Caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2HBZ
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BU of 2hbz by Molmil
Crystal structure of human caspase-1 (Arg286->Ala, Glu390->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, PHQ-VAD-fluoromethylketone inhibitor
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-06-14
公開日2006-06-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Common Allosteric Site and Mechanism in Caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2H65
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BU of 2h65 by Molmil
Crystal strusture of caspase-3 with inhibitor Ac-VDVAD-Cho
分子名称: Ac-VDVAD-Cho, caspase-3, p12 subunit, ...
著者Fang, B, Boross, P.I, Tozser, J, Weber, I.T.
登録日2006-05-30
公開日2006-09-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition
J.Mol.Biol., 360, 2006
2HBY
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BU of 2hby by Molmil
Crystal structure of human caspase-1 (Glu390->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-06-14
公開日2006-06-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Common Allosteric Site and Mechanism in Caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
1PAU
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BU of 1pau by Molmil
Crystal structure of the complex of apopain with the tetrapeptide aldehyde inhibitor AC-DEVD-CHO
分子名称: ACE-ASP-GLU-VAL-ASJ, APOPAIN
著者Rotonda, J, Becker, J.W.
登録日1996-06-06
公開日1997-07-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis.
Nat.Struct.Biol., 3, 1996
1PYO
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BU of 1pyo by Molmil
Crystal Structure of Human Caspase-2 in Complex with Acetyl-Leu-Asp-Glu-Ser-Asp-cho
分子名称: ACETYL-LEU-ASP-GLU-SER-ASJ, Caspase-2
著者Schweizer, A, Briand, C, Grutter, M.G.
登録日2003-07-09
公開日2003-08-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway.
J.Biol.Chem., 278, 2003

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