4PS0

Caspase-8 specific unnatural amino acid peptides

Summary for 4PS0

Entry DOI	10.2210/pdb4ps0/pdb
Related	4JJ7 4JJ8 4JJE 4PRY 4PRZ 4PS1
Descriptor	Caspase-3, (BAL)LQ(HYP)(1U8) PEPTIDE (3 entities in total)
Functional Keywords	protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P42574
Total number of polymer chains	4
Total formula weight	66853.72
Authors	Wolan, D.W.,Vickers, C.J.,Gonzalez-Paez, G.E. (deposition date: 2014-03-06, release date: 2015-01-21, Last modification date: 2024-04-03)
Primary citation	Vickers, C.J.,Gonzalez-Paez, G.E.,Litwin, K.M.,Umotoy, J.C.,Coutsias, E.A.,Wolan, D.W. Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids. Acs Chem.Biol., 9:2194-2198, 2014 Cited by PubMed: 25079698 DOI: 10.1021/cb5004256 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.63 Å)

Structure validation