4PS0

Caspase-8 specific unnatural amino acid peptides

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Caspase-3	polymer	285	32722.1	2	UniProt (P42574) Pfam (PF00656)	Homo sapiens (human)	CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, Caspase-3 subunit p17, Caspase-3 subunit p12
2	C, D (C, D)	(BAL)LQ(HYP)(1U8) PEPTIDE	polymer	5	704.8	2
3	E, F, G (A, B, D)	water	water		18.0	476	Chemie (HOH)

Sequence modifications

A, B: 1 - 277 (UniProt: P42574)

PDB	External Database	Details
Gln 278	-	expression tag
Leu 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag
His 284	-	expression tag
His 285	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	66853.7
All*	Total formula weight	66853.7

*Water molecules are not included.