6CKZ
Human caspase-3 in complex with Ac-DW3-KE
Summary for 6CKZ
Entry DOI | 10.2210/pdb6ckz/pdb |
Related PRD ID | PRD_002449 |
Descriptor | Caspase-3 subunit p17, Caspase-3 subunit p12, ACE-1MH-ASP-B3L-PHE-1U8, ... (4 entities in total) |
Functional Keywords | caspase-3, inhibitor, apoptosis, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 33584.03 |
Authors | Solania, A.T.,Gonzalez-Paez, G.E.,Wolan, D.W. (deposition date: 2018-03-01, release date: 2019-03-06, Last modification date: 2023-11-15) |
Primary citation | Solania, A.,Gonzalez-Paez, G.E.,Wolan, D.W. Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3. Acs Chem.Biol., 14:2463-2470, 2019 Cited by PubMed: 31334631DOI: 10.1021/acschembio.9b00564 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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