4PRZ
Caspase-8 specific unnatural amino acid peptides
Summary for 4PRZ
| Entry DOI | 10.2210/pdb4prz/pdb |
| Related | 4JJ7 4JJ8 4JJE 4PRY 4PS0 4PS1 |
| Descriptor | Caspase-8, (ACE)LET(1U8) PEPTIDE, DITHIANE DIOL, ... (4 entities in total) |
| Functional Keywords | protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q14790 |
| Total number of polymer chains | 2 |
| Total formula weight | 32400.79 |
| Authors | Wolan, D.W.,Vickers, C.J.,Gonzalez-Paez, G.E. (deposition date: 2014-03-06, release date: 2015-01-21, Last modification date: 2023-12-06) |
| Primary citation | Vickers, C.J.,Gonzalez-Paez, G.E.,Litwin, K.M.,Umotoy, J.C.,Coutsias, E.A.,Wolan, D.W. Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids. Acs Chem.Biol., 9:2194-2198, 2014 Cited by PubMed: 25079698DOI: 10.1021/cb5004256 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.123 Å) |
Structure validation
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