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4QUD

Caspase-3 T140F

Summary for 4QUD
Entry DOI10.2210/pdb4qud/pdb
Related4QTX 4QTY 4QU0 4QU5 4QU8 4QU9 4QUA 4QUB 4QUE 4QUG 4QUH 4QUI 4QUJ 4QUL
Related PRD IDPRD_000238
DescriptorCaspase-3, ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR (3 entities in total)
Functional Keywordsallosteric network, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P42574
Total number of polymer chains4
Total formula weight64465.90
Authors
Cade, C.,Swartz, P.D.,MacKenzie, S.H.,Clark, A.C. (deposition date: 2014-07-10, release date: 2014-11-05, Last modification date: 2017-11-22)
Primary citationCade, C.,Swartz, P.,MacKenzie, S.H.,Clark, A.C.
Modifying caspase-3 activity by altering allosteric networks.
Biochemistry, 53:7582-7595, 2014
Cited by
PubMed: 25343534
DOI: 10.1021/bi500874k
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.995 Å)
Structure validation

217705

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