PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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6WE8	YTH domain of human YTHDC1 分子名称: 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... 著者 Horton, J.R, Cheng, X. 登録日 2020-04-01 公開日 2020-07-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA. Nucleic Acids Res., 48, 2020
7JRE	Crystal structure of EV-D68 2A protease C107A mutant 分子名称: Protease 2A, ZINC ION 著者 Liu, C, Lee, M.-Y, Liu, W, Wang, J. 登録日 2020-08-12 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of EV-D68 2A protease C107A mutant To Be Published
6E5Z	Crystal structure of human DJ-1 with a natural modification on Cys-106 分子名称: CHLORIDE ION, Protein/nucleic acid deglycase DJ-1 著者 Shumilin, I.A, Shumilina, S.V, Minor, W. 登録日 2018-07-23 公開日 2018-08-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 A transient post-translational modification of active site cysteine alters binding properties of the parkinsonism protein DJ-1. Biochem. Biophys. Res. Commun., 504, 2018
4KIF	Crystal structure of methyltransferase from Streptomyces hygroscopicus complexed with phenylpyruvic acid 分子名称: (2R)-2-hydroxy-3-phenylpropanoic acid, 3-PHENYLPYRUVIC ACID, CALCIUM ION, ... 著者 Liu, Y.C, Zou, X.W, Chan, H.C, Huang, C.J, Li, T.L. 登録日 2013-05-02 公開日 2014-05-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase Acta Crystallogr.,Sect.D, 70, 2014
7JVS	Crystal Structure of an Essential Ribosomal Processing Protease Prp from S. aureus in complex with a Substrate Peptide 分子名称: CALCIUM ION, L27 ribosomal peptide, NICKEL (II) ION, ... 著者 Wright, H.T, Peterson, D. 登録日 2020-08-22 公開日 2021-09-01 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of an Essential Ribosomal Processing Protease Prp from S. aureus in complex with a Substrate Peptide To be published
6WIV	Structure of human GABA(B) receptor in an inactive state 分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-{[(9Z)-octadec-9-enoyl]oxy}propyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Park, J, Fu, Z, Frangaj, A, Liu, J, Mosyak, L, Shen, T, Slavkovich, V.N, Ray, K.M, Taura, J, Cao, B, Geng, Y, Zuo, H, Kou, Y, Grassucci, R, Chen, S, Liu, Z, Lin, X, Williams, J.P, Rice, W.J, Eng, E.T, Huang, R.K, Soni, R.K, Kloss, B, Yu, Z, Javitch, J.A, Hendrickson, W.A, Slesinger, P.A, Quick, M, Graziano, J, Yu, H, Fiehn, O, Clarke, O.B, Frank, J, Fan, Q.R. 登録日 2020-04-10 公開日 2020-07-01 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of human GABABreceptor in an inactive state. Nature, 584, 2020
7JT8	Apo structure of a pseudomurein peptide ligase type E from Methanothermus fervidus 分子名称: MAGNESIUM ION, Mur ligase middle domain protein, SULFATE ION 著者 Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. 登録日 2020-08-17 公開日 2021-09-01 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases. Microbiology (Reading, Engl.), 168, 2022
7JQI	Structure of wild type Glyoxylate/Hydroxypyruvate reductase A from Escherichia Coli in complex with alpha-ketoglutarate and NADP+ 分子名称: 2-OXOGLUTARIC ACID, Glyoxylate/hydroxypyruvate reductase A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Vuksanovic, N, Silvaggi, N.R. 登録日 2020-08-11 公開日 2021-09-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of wild type Glyoxylate/Hydroxypyruvate reductase A from Escherichia Coli in complex with alpha-ketoglutarate and NADP+ To Be Published
6E99	Crystal structure of Protein Kinase A in complex with the PKI peptide and an amino-pyridinylbenzamide based inhibitor. 分子名称: 2-[(2-aminoethyl)amino]-N-[(1R)-1-(3-methoxyphenyl)ethyl]-4-(pyridin-4-yl)benzamide, PKI peptide, cAMP-dependent protein kinase catalytic subunit alpha 著者 Judge, R.A, Hobson, A.D. 登録日 2018-07-31 公開日 2018-11-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure Based Drug Design. J. Med. Chem., 61, 2018
7JQH	Structure of wild type Glyoxylate/Hydroxypyruvate reductase A from Escherichia Coli in complex with phosphate and NADP+ 分子名称: GLYCEROL, Glyoxylate/hydroxypyruvate reductase A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Vuksanovic, N, Silvaggi, N.R. 登録日 2020-08-11 公開日 2021-09-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of wild type Glyoxylate/Hydroxypyruvate reductase A from Escherichia Coli in complex with phosphate and NADP+ To Be Published
6WHF	class C beta-lactamase from Escherichia coli in complex with cephalothin 分子名称: (2R)-5-[(acetyloxy)methyl]-2-{(1R)-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase 著者 Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-04-08 公開日 2020-04-22 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 class C beta-lactamase from Escherichia coli in complex with Cephalothin To Be Published
4PLD	Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, in its apo State Bound to a Fragment of Human TIF-2 分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Nuclear receptor coactivator 2, Nuclear receptor subfamily 5 group A member 2 著者 Musille, P.M, Ortlund, E.A. 登録日 2014-05-16 公開日 2015-12-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Unexpected Allosteric Network Contributes to LRH-1 Co-regulator Selectivity. J.Biol.Chem., 291, 2016
1ZAH	Fructose-1,6-bisphosphate aldolase from rabbit muscle 分子名称: Fructose-bisphosphate aldolase A 著者 St-Jean, M, Lafrance-Vanasse, J, Liotard, B, Sygusch, J. 登録日 2005-04-06 公開日 2005-05-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 High Resolution Reaction Intermediates of Rabbit Muscle Fructose-1,6-bisphosphate Aldolase: substrate cleavage and induced fit. J.Biol.Chem., 280, 2005
7JQJ	Structure of W45F Glyoxylate/Hydroxypyruvate reductase A from Escherichia Coli in complex with NADP+ 分子名称: Glyoxylate/hydroxypyruvate reductase A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Vuksanovic, N, Silvaggi, N.R. 登録日 2020-08-11 公開日 2021-09-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of W45F Glyoxylate/Hydroxypyruvate reductase A from Escherichia Coli in complex with NADP+ To Be Published
5C6F	Crystal structures of ferritin mutants reveal side-on binding to diiron and end-on cleavage of oxygen 分子名称: Bacterial non-heme ferritin, FE (III) ION, IMIDAZOLE 著者 Kim, S, Kim, K.H, Seok, J.H, Park, Y.H, Jung, S.W, Chung, Y.B, Lee, D.B, Lee, J.H, Han, K.R, Cho, A.E, Lee, C, Chung, M.S. 登録日 2015-06-23 公開日 2016-07-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis of Novel Iron-Uptake Route and Reaction Intermediates in Ferritins from Gram-Negative Bacteria. J. Mol. Biol., 428, 2016
6ECX	StiE O-MT residues 942-1257 分子名称: GLYCEROL, S-ADENOSYLMETHIONINE, StiE protein 著者 Skiba, M.A, Bivins, M.B, Smith, J.L. 登録日 2018-08-08 公開日 2018-12-12 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis of Polyketide Synthase O-Methylation. ACS Chem. Biol., 13, 2018
6EEA	Bioreductive 4-hydroxy-3-nitro-5-ureido-benzenesulfonamides selectively target the tumor-associated carbonic anhydrase isoforms IX and XII and show hypoxia-enhanced cytotoxicity against human cancer cell lines. 分子名称: 4-hydroxy-3-nitro-5-({[4-(trifluoromethyl)phenyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Singh, S, McKenna, R, Supuran, C.T, Nocentini, A, Lomelino, C, Lucarini, E, Bartolucci, G, Mannelli, L.D.C, Ghelardini, C, Gratteri, P. 登録日 2018-08-13 公開日 2018-11-28 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 4-Hydroxy-3-nitro-5-ureido-benzenesulfonamides Selectively Target the Tumor-Associated Carbonic Anhydrase Isoforms IX and XII Showing Hypoxia-Enhanced Antiproliferative Profiles. J. Med. Chem., 61, 2018
4PNX	Crystal structure of the complex of lactoperoxidase with bromo methane at 2.41 angstrom resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BROMOMETHANE, CALCIUM ION, ... 著者 Sirohi, H.V, Tyagi, T.K, Singh, A.K, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. 登録日 2014-02-22 公開日 2014-03-12 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structure of bovine lactoperoxidase with a partially linked heme moiety at 1.98 angstrom resolution. Biochim.Biophys.Acta, 1865, 2017
6X4T	Crystal structure of ICOS-L in complex with Prezalumab and VNAR domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Rujas, E, Sicard, T, Julien, J.P. 登録日 2020-05-23 公開日 2020-10-14 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies. Nat Commun, 11, 2020
6X5E	Crystal structure of a Lewis-binding Fab (ch88.2) 分子名称: NICKEL (II) ION, ch88.2 Fab heavy chain, ch88.2 Fab light chain 著者 Soliman, C, Ramsland, P.A. 登録日 2020-05-26 公開日 2020-08-26 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Molecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody. Biochem.J., 477, 2020
6EHR	The crystal structure of the human LAMTOR-RagA CTD-RagC CTD complex 分子名称: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... 著者 Scheffzek, K, Naschberger, A. 登録日 2017-09-14 公開日 2017-10-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.898 Å) 主引用文献 Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling. Science, 358, 2017
5CA2	CONFORMATIONAL MOBILITY OF HIS-64 IN THE THR-200 (RIGHT ARROW) SER MUTANT OF HUMAN CARBONIC ANHYDRASE II 分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION 著者 Alexander, R.S, Christianson, D.W. 登録日 1991-06-08 公開日 1992-10-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Conformational mobility of His-64 in the Thr-200----Ser mutant of human carbonic anhydrase II. Biochemistry, 30, 1991
1ZKY	Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-3M and A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide 分子名称: 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, Estrogen receptor, Nuclear receptor coactivator 2 著者 Rajan, S.S, Hsieh, R.W, Sharma, S.K, Hahm, J.B, Nettles, K.W, Greene, G.L. 登録日 2005-05-04 公開日 2006-05-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J.Biol.Chem., 281, 2006
6WER	DENV2 NS1 in complex with neutralizing 2B7 Fab fragment 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 Fab heavy chain, 2B7 Fab light chain, ... 著者 Akey, D.L, Smith, J.L. 登録日 2020-04-02 公開日 2020-12-23 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.96 Å) 主引用文献 Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction. Science, 371, 2021
5CAC	REFINED STRUCTURE OF HUMAN CARBONIC ANHYDRASE II AT 2.0 ANGSTROMS RESOLUTION 分子名称: CARBONIC ANHYDRASE FORM C, SULFITE ION, ZINC ION 著者 Lindahl, M, Habash, D, Harrop, S, Helliwell, D.R, Liljas, A. 登録日 1991-09-05 公開日 1994-01-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins, 4, 1988

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