4PLD

Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, in its apo State Bound to a Fragment of Human TIF-2

Summary for 4PLD

• Entry DOI: 10.2210/pdb4pld/pdb
• Related: 4PLE
• Descriptor: Nuclear receptor subfamily 5 group A member 2, Nuclear receptor coactivator 2, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ... (4 entities in total)
• Functional Keywords: nuclear receptor, apo, transcription
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : O00482 Q15596
• Total number of polymer chains: 2
• Total formula weight: 30595.48

Authors

Musille, P.M.,Ortlund, E.A. (deposition date: 2014-05-16, release date: 2015-12-16, Last modification date: 2023-09-27)

• Primary citation: Musille, P.M.,Kossmann, B.R.,Kohn, J.A.,Ivanov, I.,Ortlund, E.A.; Unexpected Allosteric Network Contributes to LRH-1 Co-regulator Selectivity.; J.Biol.Chem., 291:1411-1426, 2016; PubMed: 26553876; DOI: 10.1074/jbc.M115.662874

Experimental method

X-RAY DIFFRACTION (1.75 Å)