4PLD
Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, in its apo State Bound to a Fragment of Human TIF-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor subfamily 5 group A member 2 | polymer | 245 | 28271.7 | 1 | UniProt (O00482) Pfam (PF00104) | Homo sapiens (Human) | Alpha-1-fetoprotein transcription factor,B1-binding factor,hB1F,CYP7A promoter-binding factor,Hepatocytic transcription factor,Liver receptor homolog 1,LRH-1 |
| 2 | B (B) | Nuclear receptor coactivator 2 | polymer | 14 | 1708.9 | 1 | UniProt (Q15596) | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | C (A) | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE | non-polymer | 614.9 | 1 | Chemie (CPS) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence modifications
A: 301 - 541 (UniProt: O00482)
| PDB | External Database | Details |
|---|---|---|
| Ala 297 | - | expression tag |
| Ala 298 | - | expression tag |
| Ala 299 | - | expression tag |
| Ser 300 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29980.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 614.9 | |
| All* | Total formula weight | 30595.5 |
