4PLE
Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, Bound to an E. Coli Phospholipid and a Fragment of TIF-2
Summary for 4PLE
Entry DOI | 10.2210/pdb4ple/pdb |
Related | 4PLD |
Descriptor | Nuclear receptor subfamily 5 group A member 2, Nuclear receptor coactivator 2, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ... (5 entities in total) |
Functional Keywords | nuclear receptor, phospholipid, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 130140.65 |
Authors | Ortlund, E.A.,Musille, P.M. (deposition date: 2014-05-16, release date: 2015-12-16, Last modification date: 2023-09-27) |
Primary citation | Musille, P.M.,Kossmann, B.R.,Kohn, J.A.,Ivanov, I.,Ortlund, E.A. Unexpected Allosteric Network Contributes to LRH-1 Co-regulator Selectivity. J.Biol.Chem., 291:1411-1426, 2016 Cited by PubMed: 26553876DOI: 10.1074/jbc.M115.662874 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.752 Å) |
Structure validation
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