4PLE
Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, Bound to an E. Coli Phospholipid and a Fragment of TIF-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Nuclear receptor subfamily 5 group A member 2 | polymer | 245 | 28271.7 | 4 | UniProt (O00482) Pfam (PF00104) | Homo sapiens (Human) | Alpha-1-fetoprotein transcription factor,B1-binding factor,hB1F,CYP7A promoter-binding factor,Hepatocytic transcription factor,Liver receptor homolog 1,LRH-1 |
| 2 | B, D, F, H (B, D, F, H) | Nuclear receptor coactivator 2 | polymer | 14 | 1708.9 | 4 | UniProt (Q15596) | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | I, M, P, V (A, C, E, G) | L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE | non-polymer | 709.9 | 4 | Chemie (EPH) PubChem (46936564) PubChem (4474776) PubChem (5288167) PubChem (6323300) PubChem (168313614) | |||
| 4 | J, K, L, N, O... (A, C, E, G) | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE | non-polymer | 614.9 | 12 | Chemie (CPS) PubChem (16396400) PubChem (18397788) PubChem (177530666) PubChem (24883538) PubChem (457060) PubChem (44120060) PubChem (44450441) PubChem (50987450) PubChem (51028881) PubChem (51028882) PubChem (53393728) PubChem (3659871) PubChem (58528211) PubChem (53229977) PubChem (107670) PubChem (71774074) PubChem (9895216) PubChem (10371606) PubChem (90488808) PubChem (91746229) PubChem (91809267) PubChem (102565428) PubChem (122361936) PubChem (122362044) PubChem (131632459) PubChem (133645855) PubChem (137704711) PubChem (146159681) | |||
| 5 | AA, BA, CA, DA, Y... (D, E, G, H, A...) | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 301 - 541 (UniProt: O00482)
| PDB | External Database | Details |
|---|---|---|
| Ala 297 | - | expression tag |
| Ala 298 | - | expression tag |
| Ala 299 | - | expression tag |
| Ser 300 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 119922.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 10218.3 | |
| All* | Total formula weight | 130140.7 |
