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4PLE

Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, Bound to an E. Coli Phospholipid and a Fragment of TIF-2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, C, E, G)
Nuclear receptor subfamily 5 group A member 2polymer24528271.74UniProt (O00482)
Pfam (PF00104)
Homo sapiens (Human)Alpha-1-fetoprotein transcription factor,B1-binding factor,hB1F,CYP7A promoter-binding factor,Hepatocytic transcription factor,Liver receptor homolog 1,LRH-1
2B, D, F, H
(B, D, F, H)
Nuclear receptor coactivator 2polymer141708.94UniProt (Q15596)Homo sapiensNCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2
3I, M, P, V
(A, C, E, G)
L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINEnon-polymer709.94Chemie (EPH)
4J, K, L, N, O...
(A, C, E, G)
3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATEnon-polymer614.912Chemie (CPS)
5AA, BA, CA, DA, Y...
(D, E, G, H, A...)
waterwater18.0381Chemie (HOH)
Sequence modifications
A, C, E, G: 301 - 541 (UniProt: O00482)
PDBExternal DatabaseDetails
Ala 297-expression tag
Ala 298-expression tag
Ala 299-expression tag
Ser 300-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight119922.4
Non-Polymers*Number of molecules16
Total formula weight10218.3
All*Total formula weight130140.7
*Water molecules are not included.

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PDB entries from 2025-12-24

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