6E5Z

Crystal structure of human DJ-1 with a natural modification on Cys-106

Summary for 6E5Z

Entry DOI	10.2210/pdb6e5z/pdb
Related	3CZA
Descriptor	Protein/nucleic acid deglycase DJ-1, CHLORIDE ION (3 entities in total)
Functional Keywords	the exact function of this protein is still unknown, hydrolase, unknown function
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	20174.12
Authors	Shumilin, I.A.,Shumilina, S.V.,Minor, W. (deposition date: 2018-07-23, release date: 2018-08-01, Last modification date: 2023-10-11)
Primary citation	Mussakhmetov, A.,Shumilin, I.A.,Nugmanova, R.,Shabalin, I.G.,Baizhumanov, T.,Toibazar, D.,Khassenov, B.,Minor, W.,Utepbergenov, D. A transient post-translational modification of active site cysteine alters binding properties of the parkinsonism protein DJ-1. Biochem. Biophys. Res. Commun., 504:328-333, 2018 Cited by PubMed: 30190129 DOI: 10.1016/j.bbrc.2018.08.190 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation