Crystal structures of ferritin mutants reveal side-on binding to diiron and end-on cleavage of oxygen

Summary for 5C6F

DescriptorBacterial non-heme ferritin, FE (III) ION, IMIDAZOLE, ... (4 entities in total)
Functional Keywordsferritin, mutant, ferroxidase center, novel iron uptake route, cleavage of oxygen, oxidoreductase
Biological sourceHelicobacter pylori
Total number of polymer chains12
Total molecular weight241472.32
Kim, S.,Kim, K.H.,Seok, J.H.,Park, Y.H.,Jung, S.W.,Chung, Y.B.,Lee, D.B.,Lee, J.H.,Han, K.R.,Cho, A.E.,Lee, C.,Chung, M.S. (deposition date: 2015-06-23, release date: 2016-07-27, Last modification date: 2020-02-19)
Primary citation
Kim, S.,Lee, J.H.,Seok, J.H.,Park, Y.H.,Jung, S.W.,Cho, A.E.,Lee, C.,Chung, M.S.,Kim, K.H.
Structural Basis of Novel Iron-Uptake Route and Reaction Intermediates in Ferritins from Gram-Negative Bacteria.
J. Mol. Biol., 428:5007-5018, 2016
PubMed: 27777002 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2016.10.022
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2024 0.4% 1.7% 1.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16