6X5E

Crystal structure of a Lewis-binding Fab (ch88.2)

Summary for 6X5E

Entry DOI	10.2210/pdb6x5e/pdb
Descriptor	ch88.2 Fab light chain, ch88.2 Fab heavy chain, NICKEL (II) ION, ... (4 entities in total)
Functional Keywords	immunoglobulin, chimeric antibody, antigen binding fragment, lewis-binding antibody, immune system
Biological source	Mus musculus More
Total number of polymer chains	4
Total formula weight	96327.39
Authors	Soliman, C.,Ramsland, P.A. (deposition date: 2020-05-26, release date: 2020-08-26, Last modification date: 2023-10-18)
Primary citation	Soliman, C.,Guy, A.J.,Chua, J.X.,Vankemmelbeke, M.,McIntosh, R.S.,Eastwood, S.,Truong, V.K.,Elbourne, A.,Spendlove, I.,Durrant, L.G.,Ramsland, P.A. Molecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody. Biochem.J., 477:3219-3235, 2020 Cited by PubMed: 32789497 DOI: 10.1042/BCJ20200454 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation