PDB: 2956 件ウェブページステータス検索Chemie searchBIRD

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5U16	Structure of human MR1-2-OH-1-NA in complex with human MAIT A-F7 TCR 分子名称: 2-hydroxynaphthalene-1-carbaldehyde, Beta-2-microglobulin, CHLORIDE ION, ... 著者 Keller, A.N, Birkinshaw, R.W, Rossjohn, J. 登録日 2016-11-27 公開日 2017-02-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nat. Immunol., 18, 2017
5U4Y	IgG Fc bound to 3 helix of the B-domain from Protein A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 fc, Immunoglobulin G-binding protein A, ... 著者 Ultsch, M.H, Eigenbrot, C. 登録日 2016-12-06 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4994 Å) 主引用文献 3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix. Protein Eng. Des. Sel., 30, 2017
5U6Q	Structure of human MR1-3-F-SA in complex with human MAIT A-F7 TCR 分子名称: 3-methanoyl-2-oxidanyl-benzoic acid, ACETATE ION, Beta-2-microglobulin, ... 著者 Keller, A.N, Rossjohn, J. 登録日 2016-12-08 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nat. Immunol., 18, 2017
5UGY	Influenza hemagglutinin in complex with a neutralizing antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH65 heavy chain, ... 著者 Whittle, J.R.R, Jenni, S, Harrison, S.C. 登録日 2017-01-10 公開日 2017-01-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.801 Å) 主引用文献 Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin. Proc. Natl. Acad. Sci. U.S.A., 108, 2011
5UG0	Human antibody H2897 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2897 heavy chain, ... 著者 Raymond, D.D, Caradonna, T, Schmidt, A.G, Harrison, S.C. 登録日 2017-01-06 公開日 2017-05-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface. J. Mol. Biol., 429, 2017
5V4N	Structure of HLA-DR1 with bound alpha3(135-145) peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, alpha3(135-145)-HLA-DRB1*01:01 著者 Petersen, J, Rossjohn, J. 登録日 2017-03-10 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.405 Å) 主引用文献 Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Nature, 545, 2017
5V5M	Crystal structure of HLA-B*5701 complex with HIV-1 gag derived peptide TW10 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... 著者 Li, X, Wang, J.-H. 登録日 2017-03-14 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.878 Å) 主引用文献 Crystal structure of HLA-B*5801 with a TW10 HIV Gag epitope reveals a novel mode of peptide presentation. Cell. Mol. Immunol., 14, 2017
5VVP	HLA-B*57:03 presenting LSSPVTKSW 分子名称: Beta-2-microglobulin, LEU-SER-SER-PRO-VAL-THR-LYS-SER-TRP, MHC class I antigen 著者 Pymm, P, Rossjohn, J, Vivian, J.P. 登録日 2017-05-19 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun, 9, 2018
5W1V	Structure of the HLA-E-VMAPRTLIL/GF4 TCR complex 分子名称: Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ... 著者 Gras, S, Walpole, N, Farenc, C, Rossjohn, J. 登録日 2017-06-04 公開日 2017-10-04 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors. J. Biol. Chem., 292, 2017
5VGD	Crystal Structure of HLA-C*0501 in complex with SAE 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, Cw-5 alpha chain, ... 著者 Gras, S, Rossjohn, J. 登録日 2017-04-11 公開日 2017-05-31 最終更新日 2017-07-12 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structural and regulatory diversity shape HLA-C protein expression levels. Nat Commun, 8, 2017
5W42	Crystal structure of human monoclonal antibody H3v-47 in complex with influenza virus hemagglutinin from A/Minnesota/11/2010 (H3N2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab H3v-47 heavy chain, ... 著者 Zhang, H, Wilson, I.A. 登録日 2017-06-08 公開日 2018-07-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.569 Å) 主引用文献 A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun, 9, 2018
5W1M	MACV GP1 CR1-07 Fab complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-07 Fab heavy chain, ... 著者 Raymond, D.D, Clark, L.E, Abraham, J. 登録日 2017-06-03 公開日 2018-05-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.91 Å) 主引用文献 Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nat Commun, 9, 2018
5VUD	HLA-B*57:01 presenting LSSPVTKSW 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... 著者 Pymm, P, Rossjohn, J, Vivian, J.P. 登録日 2017-05-19 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun, 9, 2018
5VLP	PCSK9 complex with LDLR antagonist peptide and Fab7G7 分子名称: Fab7G7 heavy chain, Fab7G7 light chain, LDLR antagonist peptide, ... 著者 Eigenbrot, C, Ultsch, M. 登録日 2017-04-25 公開日 2017-08-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists. Nat. Struct. Mol. Biol., 24, 2017
5VWD	HLA-B*57:03 presenting LTVQVARVW 分子名称: Beta-2-microglobulin, MHC class I antigen, Noamer peptide: LEU-THR-VAL-GLN-VAL-ALA-ARG-VAL-TRP 著者 Pymm, P, Rossjohn, J, Vivian, J.P. 登録日 2017-05-21 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nat Commun, 9, 2018
5VOD	Crystal structure of HCMV Pentamer in complex with neutralizing antibody 9I6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... 著者 Malito, E, Chandramouli, S. 登録日 2017-05-02 公開日 2017-07-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (5.9 Å) 主引用文献 Structural basis for potent antibody-mediated neutralization of human cytomegalovirus. Sci Immunol, 2, 2017
5VEB	Crystal structure of a Fab binding to extracellular domain 5 of Cadherin-6 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Cadherin-6, anti-CDH6 Fab heavy chain, ... 著者 Zhu, X, Bialucha, C.U, London, A, Clark, K, Hu, T. 登録日 2017-04-04 公開日 2017-06-07 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers. Cancer Discov, 7, 2017
5VIG	Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII 分子名称: CITRATE ANION, Fab heavy chain, Fab light chain, ... 著者 Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J. 登録日 2017-04-16 公開日 2017-05-03 最終更新日 2017-05-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico. Cell, 169, 2017
5VJ6	BG505 SOSIP.664 in complex with broadly neutralizing antibodies PG9 and 8ANC195 分子名称: 8ANC195 Fab heavy chain, 8ANC195 Fab light chain, Envelope glycoprotein gp160, ... 著者 Wang, H, Bjorkman, P.J. 登録日 2017-04-18 公開日 2017-06-21 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (11.5 Å) 主引用文献 Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies. Elife, 6, 2017
5VOB	Crystal structure of HCMV Pentamer in complex with neutralizing antibody 8I21 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... 著者 Malito, E, Chandramouli, S. 登録日 2017-05-02 公開日 2017-07-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Structural basis for potent antibody-mediated neutralization of human cytomegalovirus. Sci Immunol, 2, 2017
5VZY	Crystal structure of crenezumab Fab in complex with Abeta 分子名称: Amyloid beta A4 protein, Crenezumab Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Crenezumab Fab light chain,Immunoblobulin light chain 著者 Ultsch, M, Wang, W. 登録日 2017-05-29 公開日 2017-08-09 最終更新日 2017-09-13 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin. Sci Rep, 6, 2016
5W08	A/Texas/50/2012(H3N2) Influenza hemagglutinin in complex with K03.12 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 McCarthy, K.R, Harrison, S.C. 登録日 2017-05-30 公開日 2018-02-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity, 48, 2018
5V5L	Crystal structure of HLA-B*5801 complex with HIV-1 gag derived peptide TW10 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-58 alpha chain, ... 著者 Li, X, Wang, J.-H. 登録日 2017-03-14 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 Crystal structure of HLA-B*5801 with a TW10 HIV Gag epitope reveals a novel mode of peptide presentation. Cell. Mol. Immunol., 14, 2017
5UJT	Crystal structure of human HLA-DQ8 in complex with insulin mimotope binding in register 3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-beta-1, ... 著者 Wang, Y, Dai, S. 登録日 2017-01-18 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5V4M	Structure of HLA-DR15 with bound alpha3(135-145) peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, ... 著者 Petersen, J, Rossjohn, J. 登録日 2017-03-10 公開日 2017-05-03 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Nature, 545, 2017

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