5VGD

Crystal Structure of HLA-C*0501 in complex with SAE

Summary for 5VGD

• Entry DOI: 10.2210/pdb5vgd/pdb
• Related: 5vge
• Descriptor: HLA class I histocompatibility antigen, Cw-5 alpha chain, Beta-2-microglobulin, SER-ALA-GLU-PRO-VAL-PRO-LEU-GLN-LEU, ... (4 entities in total)
• Functional Keywords: hla, immune system, hla-c
• Biological source: Homo sapiens (Human); More
• Cellular location: Membrane; Single-pass type I membrane protein: Q9TNN7; Secreted . Note=(Microbial infection) In the presence of M: P61769
• Total number of polymer chains: 3
• Total formula weight: 44936.84

Authors

Gras, S.,Rossjohn, J. (deposition date: 2017-04-11, release date: 2017-05-31, Last modification date: 2017-07-12)

• Primary citation: Kaur, G.,Gras, S.,Mobbs, J.I.,Vivian, J.P.,Cortes, A.,Barber, T.,Kuttikkatte, S.B.,Jensen, L.T.,Attfield, K.E.,Dendrou, C.A.,Carrington, M.,McVean, G.,Purcell, A.W.,Rossjohn, J.,Fugger, L.; Structural and regulatory diversity shape HLA-C protein expression levels.; Nat Commun, 8:15924-15924, 2017; PubMed: 28649982; DOI: 10.1038/ncomms15924

Experimental method

X-RAY DIFFRACTION (2.32 Å)