Summary for 5VZY
| Entry DOI | 10.2210/pdb5vzy/pdb |
| Related | 5VZX |
| Descriptor | Crenezumab Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Crenezumab Fab light chain,Immunoblobulin light chain, Amyloid beta A4 protein, ... (4 entities in total) |
| Functional Keywords | immunoglobulin, immune system |
| Biological source | Homo sapiens More |
| Cellular location | Secreted : P0DOX5 Membrane; Single-pass type I membrane protein: P05067 |
| Total number of polymer chains | 3 |
| Total formula weight | 48820.30 |
| Authors | Ultsch, M.,Wang, W. (deposition date: 2017-05-29, release date: 2017-08-09, Last modification date: 2017-09-13) |
| Primary citation | Ultsch, M.,Li, B.,Maurer, T.,Mathieu, M.,Adolfsson, O.,Muhs, A.,Pfeifer, A.,Pihlgren, M.,Bainbridge, T.W.,Reichelt, M.,Ernst, J.A.,Eigenbrot, C.,Fuh, G.,Atwal, J.K.,Watts, R.J.,Wang, W. Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin. Sci Rep, 6:39374-, 2016 Cited by PubMed: 27996029DOI: 10.1038/srep39374 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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