5VOD

Crystal structure of HCMV Pentamer in complex with neutralizing antibody 9I6

Summary for 5VOD

Entry DOI	10.2210/pdb5vod/pdb
Related	5COB 5VOC
Descriptor	Envelope glycoprotein H, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein L, ... (10 entities in total)
Functional Keywords	hcmv, neutralizing epitope, immunogen, viral entry, pentamer, vaccine, immune system, viral protein-immune system complex, viral protein/immune system
Biological source	Human cytomegalovirus (HHV-5) More
Cellular location	Virion membrane ; Single-pass type I membrane protein : Q6SW67 Virion membrane ; Peripheral membrane protein ; Extracellular side : Q68674 Virion : F5HET4
Total number of polymer chains	7
Total formula weight	237952.80
Authors	Malito, E.,Chandramouli, S. (deposition date: 2017-05-02, release date: 2017-07-05, Last modification date: 2023-10-04)
Primary citation	Chandramouli, S.,Malito, E.,Nguyen, T.,Luisi, K.,Donnarumma, D.,Xing, Y.,Norais, N.,Yu, D.,Carfi, A. Structural basis for potent antibody-mediated neutralization of human cytomegalovirus. Sci Immunol, 2:-, 2017 Cited by PubMed: 28783665 DOI: 10.1126/sciimmunol.aan1457 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (5.9 Å)

Structure validation