PDB: 46205 件ウェブページステータス検索Chemie searchBIRD

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3MC8	POTRA1-3 of the periplasmic domain of Omp85 from Anabaena 分子名称: Alr2269 protein 著者 Koenig, P, Schleiff, E, Sinning, I, Tews, I. 登録日 2010-03-28 公開日 2010-04-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Conserved properties of polypeptide transport-associated (POTRA) domains derived from cyanobacterial Omp85. J.Biol.Chem., 285, 2010
4GSY	Crystal structure of thymidylate kinase from Staphylococcus aureus bound to inhibitor. 分子名称: 4-{[(3S)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)piperidin-1-yl]methyl}-2-[3-(trifluoromethyl)phenoxy]benzoic acid, Thymidylate kinase 著者 Larsen, N.A, Olivier, N.B. 登録日 2012-08-28 公開日 2012-10-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK). J.Med.Chem., 55, 2012
4GT9	T. Maritima FDTS with FAD, dUMP and Folate. 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Mathews, I.I, Lesley, S.A, Kohen, A. 登録日 2012-08-28 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Folate binding site of flavin-dependent thymidylate synthase. Proc.Natl.Acad.Sci.USA, 109, 2012
6THC	Crystal structure of Mycobacterium smegmatis CoaB in complex with CTP and (4-hydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone 分子名称: (4-hydroxyphenyl)-[2,3,4-tris(oxidanyl)phenyl]methanone, ACETATE ION, CALCIUM ION, ... 著者 Mendes, V, Blaszczyk, M, Bryant, O, Cory-Wright, J, Blundell, T.L. 登録日 2019-11-19 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.033 Å) 主引用文献 Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site. Nat Commun, 12, 2021
6TQP	Structural insight into tanapoxvirus mediated inhibition of apoptosis 分子名称: 16L protein, Bcl-2-binding component 3, isoforms 1/2, ... 著者 Suraweera, C.D, Hinds, M.G, Kvansakul, M. 登録日 2019-12-17 公開日 2020-06-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.84940946 Å) 主引用文献 Structural insight into tanapoxvirus-mediated inhibition of apoptosis. Febs J., 287, 2020
6TQY	Crystal structure of ribonucleotide reductase NrdF L61G variant from Bacillus anthracis anaerobically soaked with Fe(II) and Mn(II) ions 分子名称: MANGANESE (II) ION, Ribonucleoside-diphosphate reductase subunit beta, SULFATE ION 著者 Grave, K, Hogbom, M. 登録日 2019-12-17 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron. J.Biol.Inorg.Chem., 25, 2020
6TTW	Crystal structure of the human METTL3-METTL14 complex bound to Compound 4 (ASI_M3M_047) 分子名称: (2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)-~{N}-piperidin-4-yl-oxolane-2-carboxamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. 登録日 2019-12-30 公開日 2020-03-04 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Small-Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer. Chemmedchem, 15, 2020
7Z8B	Structure of CRL7FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation 分子名称: Cullin-7, E3 ubiquitin-protein ligase RBX1, F-box/WD repeat-containing protein 8, ... 著者 Hopf, L.V.M, Schulman, B.A. 登録日 2022-03-17 公開日 2022-08-24 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structure of CRL7 FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation. Nat.Struct.Mol.Biol., 29, 2022
6TKY	Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42 分子名称: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL 著者 Barford, D, Fan, D, Cronin, N, Yang, J. 登録日 2019-11-29 公開日 2020-01-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10 Biorxiv, 2022
2JK3	CRYSTAL STRUCTURE OF THE HLYIIR MUTANT PROTEIN WITH RESIDUES 169-186 SUBSTITUTED BY GSSGSSG LINKER 分子名称: HEMOLYSIN II REGULATORY PROTEIN, SULFATE ION 著者 Kovalevskiy, O.V, Solonin, A.S, Antson, A.A. 登録日 2008-08-11 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Investigation of Transcriptional Regulator Hlyiir: Influence of a Disordered Region on Protein Fold and Dimerization. Proteins, 78, 2010
3MCR	Crystal structure of NADH dehydrogenase subunit C (Tfu_2693) from THERMOBIFIDA FUSCA YX-ER1 at 2.65 A resolution 分子名称: COBALT (II) ION, HEXANE-1,6-DIOL, NADH dehydrogenase, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2010-03-29 公開日 2010-05-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of NADH dehydrogenase subunit C (Tfu_2693) from THERMOBIFIDA FUSCA YX-ER1 at 2.65 A resolution To be published
6TJM	Crystal structure of an Estrogen Receptor alpha 8-mer phosphopeptide in complex with 14-3-3sigma stabilized by Pyrrolidone1 分子名称: 14-3-3 protein sigma, 5-[(2~{R})-2-(4-nitrophenyl)-4-oxidanyl-5-oxidanylidene-3-(phenylcarbonyl)-2~{H}-pyrrol-1-yl]-2-oxidanyl-benzoic acid, C-terminal phosphopeptide of human estrogen receptor alpha, ... 著者 Andrei, S.A, Bosica, F, Ottmann, C, O'Mahony, G. 登録日 2019-11-26 公開日 2020-04-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Design of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization. Chemistry, 26, 2020
6TLF	human 14-3-3 sigma isoform in complex with IMP 分子名称: 14-3-3 protein sigma, INOSINIC ACID, SULFATE ION 著者 Tassone, G, Pozzi, C, Mangani, S. 登録日 2019-12-02 公開日 2020-03-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction. Acs Chem.Biol., 15, 2020
6TLO	HUMAN CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 4,5,6-TRIBROMOBENZOTRIAZOLE 分子名称: 5,6,7-tris(bromanyl)-1~{H}-benzotriazole, CHLORIDE ION, Casein kinase II subunit alpha, ... 著者 Czapinska, H, Piasecka, A, Winiewska-Szajewska, M, Bochtler, M, Poznanski, J. 登録日 2019-12-03 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2. J.Phys.Chem.B, 125, 2021
4H1O	Crystal structure of the tyrosine phosphatase SHP-2 with D61G mutation 分子名称: 1,2-ETHANEDIOL, Tyrosine-protein phosphatase non-receptor type 11 著者 Qiu, W, Lin, A, Hutchinson, A, Romanov, V, Ruzanov, M, Thompson, C, Lam, K, Kisselman, G, Battaile, K, Chirgadze, N.Y. 登録日 2012-09-11 公開日 2013-09-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the tyrosine phosphatase SHP-2 with D61G mutation To be Published
1JUJ	Human Thymidylate Synthase Bound to dUMP and LY231514, a Pyrrolo(2,3-d)pyrimidine-based Antifolate 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, THYMIDYLATE SYNTHASE 著者 Sayre, P.H, Finer-Moore, J.S, Fritz, T.A, Biermann, D, Gates, S.B, MacKellar, W.C, Patel, V.F, Stroud, R.M. 登録日 2001-08-24 公開日 2001-09-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases. J.Mol.Biol., 313, 2001
1JW5	Structure of Maltose Bound to Open-form Maltodextrin-binding Protein in P1 Crystal 分子名称: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltodextrin-binding protein 著者 Duan, X, Quiocho, F.A. 登録日 2001-09-02 公開日 2002-01-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural evidence for a dominant role of nonpolar interactions in the binding of a transport/chemosensory receptor to its highly polar ligands. Biochemistry, 41, 2002
6TLV	HUMAN CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 5-BROMOBENZOTRIAZOLE 分子名称: 6-bromanyl-1~{H}-benzotriazole, CHLORIDE ION, Casein kinase II subunit alpha, ... 著者 Czapinska, H, Piasecka, A, Winiewska-Szajewska, M, Bochtler, M, Poznanski, J. 登録日 2019-12-03 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2. J.Phys.Chem.B, 125, 2021
7MHS	Structure of p97 (subunits A to E) with substrate engaged 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Xu, Y, Han, H, Cooney, I, Hill, C.P, Shen, P.S. 登録日 2021-04-15 公開日 2022-05-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Active conformation of the p97-p47 unfoldase complex. Nat Commun, 13, 2022
1K1A	Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family 分子名称: B-cell lymphoma 3-encoded protein 著者 Michel, F, Soler-Lopez, M, Petosa, C, Cramer, P, Siebenlist, U, Mueller, C.W. 登録日 2001-09-24 公開日 2001-11-21 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family. EMBO J., 20, 2001
5F28	Crystal structure of FAT domain of Focal Adhesion Kinase (FAK) bound to the transcription factor MEF2C 分子名称: Focal adhesion kinase 1, MEF2C 著者 Cardoso, A.C, Ambrosio, A.L.B, Dessen, A, Franchini, K.G. 登録日 2015-12-01 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 FAK Forms a Complex with MEF2 to Couple Biomechanical Signaling to Transcription in Cardiomyocytes. Structure, 24, 2016
4HGH	Crystal structure of P450 BM3 5F5 heme domain variant complexed with styrene (dataset I) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450/NADPH-P450 reductase, DI(HYDROXYETHYL)ETHER, ... 著者 Shehzad, A, Panneerselvam, S, Bocola, M, Mueller-Dieckmann, J, Wilmanns, M, Schwaneberg, U. 登録日 2012-10-08 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation. Chem.Commun.(Camb.), 49, 2013
6TQW	Crystal structure of ribonucleotide reductase NrdF from Bacillus anthracis anaerobically soaked with Fe(II) and Mn(II) ions 分子名称: MANGANESE (II) ION, Ribonucleoside-diphosphate reductase subunit beta, SULFATE ION 著者 Grave, K, Hogbom, M. 登録日 2019-12-17 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron. J.Biol.Inorg.Chem., 25, 2020
6TRR	Structural insight into tanapoxvirus mediated inhibition of apoptosis 分子名称: 16L protein, Apoptosis regulator BAX, SODIUM ION 著者 Suraweera, C.D, Hinds, M.G, Kvansakul, M. 登録日 2019-12-19 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.12007356 Å) 主引用文献 Structural insight into tanapoxvirus-mediated inhibition of apoptosis. Febs J., 287, 2020
3MP8	Crystal structure of Sgf29 tudor domain 分子名称: 4-(HYDROXYMETHYL)BENZAMIDINE, ACETIC ACID, GLYCEROL, ... 著者 Li, J, Wu, M, Ruan, J, Zang, J. 登録日 2010-04-26 公開日 2011-05-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation Embo J., 30, 2011

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