6TLO
HUMAN CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 4,5,6-TRIBROMOBENZOTRIAZOLE
Summary for 6TLO
Entry DOI | 10.2210/pdb6tlo/pdb |
Descriptor | Casein kinase II subunit alpha, 5,6,7-tris(bromanyl)-1~{H}-benzotriazole, SODIUM ION, ... (5 entities in total) |
Functional Keywords | ck2, casein kinase 2, inhibitor, bromo-benzotriazole, halogen bond, transferase-transferase inhibitor complex, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 47085.22 |
Authors | Czapinska, H.,Piasecka, A.,Winiewska-Szajewska, M.,Bochtler, M.,Poznanski, J. (deposition date: 2019-12-03, release date: 2020-12-16, Last modification date: 2024-01-24) |
Primary citation | Czapinska, H.,Winiewska-Szajewska, M.,Szymaniec-Rutkowska, A.,Piasecka, A.,Bochtler, M.,Poznanski, J. Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2. J.Phys.Chem.B, 125:2491-2503, 2021 Cited by PubMed: 33689348DOI: 10.1021/acs.jpcb.0c10264 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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