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6SCN
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BU of 6scn by Molmil
33mer structure of the Salmonella flagella MS-ring protein FliF
分子名称: Flagellar M-ring protein
著者Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M.
登録日2019-07-24
公開日2020-03-18
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation.
Nat Microbiol, 5, 2020
6SF2
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BU of 6sf2 by Molmil
Ternary complex of human bone morphogenetic protein 9 (BMP9) growth factor domain, its prodomain and extracellular domain of activin receptor-like kinase 1 (ALK1).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Growth/differentiation factor 2, Serine/threonine-protein kinase receptor R3
著者Salmon, R.M, Guo, J, Yu, M, Li, W.
登録日2019-07-31
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms.
Nat Commun, 11, 2020
7MK9
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BU of 7mk9 by Molmil
Complex structure of trailing EC of EC+EC (trailing EC-focused)
分子名称: DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ...
著者Yang, C, Murakami, K.
登録日2021-04-22
公開日2022-04-27
最終更新日2023-05-17
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
6SHC
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BU of 6shc by Molmil
Crystal structure of human IRE1 luminal domain Q105C
分子名称: Serine/threonine-protein kinase/endoribonuclease IRE1
著者Yan, Y, Ron, D.
登録日2019-08-06
公開日2020-01-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Unstructured regions in IRE1 alpha specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR.
Elife, 8, 2019
6XZF
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BU of 6xzf by Molmil
Nanobody in complex with eGFP
分子名称: Nanobody targeted against eGFP, TERBIUM(III) ION, eGFP
著者Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日2020-02-04
公開日2021-02-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Engineered nanobodies with a lanthanide binding motif for crystallographic phasing
To Be Published
6X9Z
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BU of 6x9z by Molmil
De novo design of transmembrane beta-barrels
分子名称: Transmembrane beta-barrels
著者Bera, A.K, Vorobieva, A.A, Kang, A.S, Baker, D.
登録日2020-06-03
公開日2021-02-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献De novo design of transmembrane beta barrels.
Science, 371, 2021
6XCS
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BU of 6xcs by Molmil
Erythromycin esterase mutant EreC H289N in its open conformation
分子名称: EreC
著者Zielinski, M, Berghuis, A.M.
登録日2020-06-09
公開日2021-02-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and functional insights into esterase-mediated macrolide resistance.
Nat Commun, 12, 2021
6MBF
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BU of 6mbf by Molmil
GphF Dehydratase 1
分子名称: GphF Dehydratase 1, MAGNESIUM ION
著者Dodge, G.J, Smith, J.L.
登録日2018-08-29
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.543 Å)
主引用文献Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase.
ACS Chem. Biol., 13, 2018
6XF9
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BU of 6xf9 by Molmil
Crystal structure of KSHV ORF68
分子名称: Packaging protein UL32, ZINC ION
著者Didychuk, A.L, Gates, S.N, Martin, A, Glaunsinger, B.
登録日2020-06-15
公開日2021-02-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献A pentameric protein ring with novel architecture is required for herpesviral packaging.
Elife, 10, 2021
6SDG
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BU of 6sdg by Molmil
Crystal structure of the DNA binding domain of M. polymorpha Auxin Response Factor 2 (MpARF2) in complex with High Affinity DNA
分子名称: 21-7_A, 21-7_B, Auxin response factor
著者Crespo, I, Weijers, D, Boer, D.R.
登録日2019-07-27
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Design principles of a minimal auxin response system.
Nat.Plants, 6, 2020
5WK9
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BU of 5wk9 by Molmil
R186AP450cam with CN and camphor
分子名称: CAMPHOR, CYANIDE ION, Camphor 5-monooxygenase, ...
著者Poulos, T.L, Batabyal, D.
登録日2017-07-24
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.983 Å)
主引用文献Effect of Redox Partner Binding on Cytochrome P450 Conformational Dynamics.
J. Am. Chem. Soc., 139, 2017
6SDV
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BU of 6sdv by Molmil
W-formate dehydrogenase from Desulfovibrio vulgaris - Formate reduced form
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, Formate dehydrogenase, ...
著者Oliveira, A.R, Mota, C, Mourato, C, Domingos, R.M, Santos, M.F.A, Gesto, D, Guigliarelli, B, Santos-Silva, T, Romao, M.J, Pereira, I.C.
登録日2019-07-29
公開日2020-03-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Towards the mechanistic understanding of enzymatic CO2 reduction
Acs Catalysis, 2020
6XA8
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BU of 6xa8 by Molmil
Crystal Structure of Human Scribble PDZ1:Vangl2 complex
分子名称: 1,2-ETHANEDIOL, C-terminal peptide of Vangl2, PHOSPHATE ION, ...
著者How, J.Y, Kvansakul, M.
登録日2020-06-04
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of the human Scribble-Vangl2 association in health and disease.
Biochem.J., 478, 2021
5WLH
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BU of 5wlh by Molmil
Crystal structure of LbaCas13a H328A (C2c2) bound to pre-crRNA (24-nt spacer)
分子名称: GLYCEROL, IODIDE ION, LbaCas13a H328A (C2c2), ...
著者Knott, G.J, Doudna, J.A.
登録日2017-07-26
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.80001032 Å)
主引用文献Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol., 24, 2017
6SC9
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BU of 6sc9 by Molmil
dAb3/HOIP-RBR-HOIPIN-8
分子名称: 2-[3-[2,6-bis(fluoranyl)-4-(1~{H}-pyrazol-4-yl)phenyl]-3-oxidanylidene-prop-1-enyl]-4-(1-methylpyrazol-4-yl)benzoic acid, CHLORIDE ION, E3 ubiquitin-protein ligase RNF31, ...
著者Tsai, Y.-C.I, Johansson, H, House, D, Rittinger, K.
登録日2019-07-23
公開日2019-11-27
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases.
Cell Chem Biol, 27, 2020
6X93
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BU of 6x93 by Molmil
Interleukin-10 signaling complex with IL-10RA and IL-10RB
分子名称: Interleukin-10, Interleukin-10 receptor subunit alpha, Interleukin-10 receptor subunit beta
著者Saxton, R.A, Tsutsumi, N, Gati, C, Garcia, K.C.
登録日2020-06-02
公開日2021-03-17
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10.
Science, 371, 2021
6XA6
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BU of 6xa6 by Molmil
Crystal Structure of Human Scribble PDZ3:Vangl2 Complex
分子名称: 1,2-ETHANEDIOL, Protein scribble homolog, Vang-like protein 2
著者How, J.Y, Kvansakul, M.
登録日2020-06-04
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of the human Scribble-Vangl2 association in health and disease.
Biochem.J., 478, 2021
6X90
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BU of 6x90 by Molmil
Structure of the guanine nucleotide exchange factor Sec12 bound to the small GTPase Sar1
分子名称: Guanine nucleotide-exchange factor SEC12, POTASSIUM ION, Small COPII coat GTPase SAR1
著者Joiner, A.M.N, Fromme, J.C.
登録日2020-06-02
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural basis for the initiation of COPII vesicle biogenesis.
Structure, 29, 2021
6XA7
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BU of 6xa7 by Molmil
Crystal Structure of Human Scribble PDZ2:Vangl2 complex
分子名称: 1,2-ETHANEDIOL, Protein scribble homolog, Vang-like protein 2
著者How, J.Y, Kvansakul, M.
登録日2020-06-04
公開日2021-03-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of the human Scribble-Vangl2 association in health and disease.
Biochem.J., 478, 2021
5WN0
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BU of 5wn0 by Molmil
APE1 exonuclease substrate complex with a C/G match
分子名称: DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), ...
著者Freudenthal, B.D, Whitaker, A.M.
登録日2017-07-31
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular snapshots of APE1 proofreading mismatches and removing DNA damage.
Nat Commun, 9, 2018
6XRX
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BU of 6xrx by Molmil
Crystal structure of the mosquito protein AZ1 as an MBP fusion
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein, ...
著者Pedersen, L.C, Mueller, G.A, Foo, A.C.Y.
登録日2020-07-14
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The mosquito protein AEG12 displays both cytolytic and antiviral properties via a common lipid transfer mechanism.
Proc.Natl.Acad.Sci.USA, 118, 2021
6LTR
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BU of 6ltr by Molmil
Crystal structure of Cas12i2 ternary complex with single Mg2+ bound in catalytic pocket
分子名称: 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ...
著者Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y.
登録日2020-01-23
公開日2020-10-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
6LO8
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BU of 6lo8 by Molmil
Cryo-EM structure of the TIM22 complex from yeast
分子名称: Mitochondrial import inner membrane translocase subunit TIM10, Mitochondrial import inner membrane translocase subunit TIM12, Mitochondrial import inner membrane translocase subunit TIM18, ...
著者Zhang, Y, Zhou, X, Wu, X, Li, L.
登録日2020-01-04
公開日2020-09-30
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (3.83 Å)
主引用文献Structure of the mitochondrial TIM22 complex from yeast.
Cell Res., 31, 2021
6XOC
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BU of 6xoc by Molmil
Crystal structure of glVRC01 Fab in complex with anti-idiotypic iv4 Fab
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Aljedani, S.S, Weidle, C, Pancera, M.
登録日2020-07-06
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell Rep, 35, 2021
6LU0
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Crystal structure of Cas12i2 ternary complex with 12 nt spacer
分子名称: Cas12i2, DNA (5'-D(*GP*CP*CP*GP*CP*TP*TP*TP*CP*TP*T)-3'), DNA (5'-D(*GP*CP*TP*TP*GP*CP*TP*CP*TP*GP*TP*TP*GP*AP*AP*AP*GP*CP*GP*GP*C)-3'), ...
著者Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y.
登録日2020-01-24
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020

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