4ZAO

Genetically engineered Carbonic anhydrase IX

Summary for 4ZAO

Related4YMP
DescriptorCarbonic anhydrase 2, ZINC ION (3 entities in total)
Functional Keywordsca ix mimic, lyase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm  P00918
Total number of polymer chains1
Total molecular weight29266.3
Authors
Pinard, M.A.,Aggarwal, M. (deposition date: 2015-04-13, release date: 2015-10-14, Last modification date: 2018-04-18)
Primary citation
Pinard, M.A.,Aggarwal, M.,Mahon, B.P.,Tu, C.,McKenna, R.
A sucrose-binding site provides a lead towards an isoform-specific inhibitor of the cancer-associated enzyme carbonic anhydrase IX.
Acta Crystallogr F Struct Biol Commun, 71:1352-1358, 2015
PubMed: 26457530 (PDB entries with the same primary citation)
DOI: 10.1107/S2053230X1501239X
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20530 0.5% 1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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169963
PDB entries from 2020-10-14