4R65

Ternary complex crystal structure of R258A mutant of DNA polymerase Beta

Summary for 4R65

Related4R63 4R64 4R66
DescriptorDNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... (9 entities in total)
Functional Keywordsdna polymerase beta, conformational change, enzyme mechanism, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
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Cellular locationNucleus P06746
Total number of polymer chains4
Total molecular weight48380.22
Authors
Batra, V.K.,Beard, W.A.,Wilson, S.H. (deposition date: 2014-08-22, release date: 2014-10-08, Last modification date: 2017-11-22)
Primary citation
Beard, W.A.,Shock, D.D.,Batra, V.K.,Prasad, R.,Wilson, S.H.
Substrate-induced DNA Polymerase beta Activation.
J.Biol.Chem., 289:31411-31422, 2014
PubMed: 25261471 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M114.607432
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.95 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.213401.0%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload