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4R65

Ternary complex crystal structure of R258A mutant of DNA polymerase Beta

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase betapolymer33538155.61UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (human)
2TDNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer164853.21Synthetic construct
3PDNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3')polymer103061.01Synthetic construct
4DDNA (5'-D(P*GP*TP*CP*GP*G)-3')polymer51536.01Synthetic construct
5A2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATEnon-polymer467.21Chemie (DUP)
6AMAGNESIUM IONnon-polymer24.32Chemie (MG)
7ASODIUM IONnon-polymer23.02Chemie (NA)
8ACHLORIDE IONnon-polymer35.56Chemie (CL)
9waterwater18.0393Chemie (HOH)
Sequence modifications
A: 1 - 335 (UniProt: P06746)
PDBExternal DatabaseDetails
Ala 258Arg 258engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47605.8
Non-Polymers*Number of molecules11
Total formula weight774.5
All*Total formula weight48380.2
*Water molecules are not included.

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PDB entries from 2024-03-27

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