4RIQ

Crystal structure of DPY-30 dimerization/docking domain in complex with Ash2L Sdc1-DPY-30 Interacting region (SDI)

Summary for 4RIQ

Entry DOI	10.2210/pdb4riq/pdb
Descriptor	Protein dpy-30 homolog, Set1/Ash2 histone methyltransferase complex subunit ASH2, SULFATE ION, ... (4 entities in total)
Functional Keywords	histone, chromatin, methylation, dimerization/docking module, allosteric regulator, ash2l, wdr5, rbbp5, mll1, mll2, mll3, mll4, set1a, set1b, transferase-protein binding complex, transferase/protein binding
Biological source	Homo sapiens (human) More
Cellular location	Nucleus : Q9C005 Q9UBL3
Total number of polymer chains	24
Total formula weight	126007.79
Authors	Tremblay, V.,Couture, J.-F. (deposition date: 2014-10-07, release date: 2014-12-17, Last modification date: 2024-02-28)
Primary citation	Tremblay, V.,Zhang, P.,Chaturvedi, C.P.,Thornton, J.,Brunzelle, J.S.,Skiniotis, G.,Shilatifard, A.,Brand, M.,Couture, J.F. Molecular Basis for DPY-30 Association to COMPASS-like and NURF Complexes. Structure, 22:1821-1830, 2014 Cited by PubMed: 25456412 DOI: 10.1016/j.str.2014.10.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.231 Å)

Structure validation