4RIQ

Crystal structure of DPY-30 dimerization/docking domain in complex with Ash2L Sdc1-DPY-30 Interacting region (SDI)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, D, E, G...	Protein dpy-30 homolog	polymer	56	6300.3	16	UniProt (Q9C005) Pfam (PF05186) In PDB	Homo sapiens (human)	Dpy-30-like protein, Dpy-30L
2	C, F, I, L, O...	Set1/Ash2 histone methyltransferase complex subunit ASH2	polymer	27	3054.3	8	UniProt (Q9UBL3) In PDB	Homo sapiens (human)	ASH2-like protein
3	I, K, L, O, R...	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
4		water	water		18.0	23	Chemie (HOH)

Sequence modifications

A, B, D, E, G, H, J, K, M, N, P, Q, S, T, V, Z: 45 - 99 (UniProt: Q9C005)

PDB	External Database	Details
Gly 44	-	expression tag

C, F, I, L, O, R, U, X: 509 - 524 (UniProt: Q9UBL3)

PDB	External Database	Details
Gly 504	-	expression tag
Ala 505	-	expression tag
Met 506	-	expression tag
Gly 507	-	expression tag
Ser 508	-	expression tag
Glu 525	-	expression tag
Asn 526	-	expression tag
Leu 527	-	expression tag
Tyr 528	-	expression tag
Phe 529	-	expression tag
Gln 530	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	125239.3
Non-Polymers*	Number of molecules	8
	Total formula weight	768.5
All*	Total formula weight	126007.8

*Water molecules are not included.