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1BKO
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THERMOSTABLE THYMIDYLATE SYNTHASE A FROM BACILLUS SUBTILIS
分子名称: THYMIDYLATE SYNTHASE A
著者Stout, T.J, Schellenberger, U, Santi, D.V, Stroud, R.M.
登録日1998-07-09
公開日1999-02-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structures of a unique thermal-stable thymidylate synthase from Bacillus subtilis.
Biochemistry, 37, 1998
1BKW
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p-Hydroxybenzoate hydroxylase (phbh) mutant with cys116 replaced by ser (c116s) and arg44 replaced by lys (r44k), in complex with fad and 4-hydroxybenzoic acid
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE)
著者Eppink, M.H, Schreuder, H.A, Van Berkel, W.J.
登録日1998-07-13
公開日1998-07-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and function of mutant Arg44Lys of 4-hydroxybenzoate hydroxylase implications for NADPH binding.
Eur.J.Biochem., 231, 1995
1BM3
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IMMUNOGLOBULIN OPG2 FAB-PEPTIDE COMPLEX
分子名称: IMMUNOGLOBULIN OPG2 FAB, CONSTANT DOMAIN, VARIABLE DOMAIN
著者Kodandapani, R, Veerapandian, L, Ni, C.Z, Chiou, C.-K, Whital, R, Kunicki, T.J, Ely, K.R.
登録日1999-04-15
公開日1999-04-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational change in an anti-integrin antibody: structure of OPG2 Fab bound to a beta 3 peptide.
Biochem.Biophys.Res.Commun., 251, 1998
1BMK
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB218655
分子名称: 4-(FLUOROPHENYL)-1-CYCLOPROPYLMETHYL-5-(2-AMINO-4-PYRIMIDINYL)IMIDAZOLE, PROTEIN (MAP KINASE P38)
著者Wang, Z, Canagarajah, B, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-07-23
公開日1999-07-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BNK
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HUMAN 3-METHYLADENINE DNA GLYCOSYLASE COMPLEXED TO DNA
分子名称: DNA (5'-D(*GP*AP*CP*AP*TP*GP*YRRP*TP*TP*GP*CP*CP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), PROTEIN (3-METHYLADENINE DNA GLYCOSYLASE)
著者Lau, A.Y, Schaerer, O.D, Samson, L, Verdine, G.L, Ellenberger, T.
登録日1998-07-29
公開日1998-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision.
Cell(Cambridge,Mass.), 95, 1998
1BWK
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OLD YELLOW ENZYME (OYE1) MUTANT H191N
分子名称: FLAVIN MONONUCLEOTIDE, PROTEIN (NADPH DEHYDROGENASE 1)
著者Brown, B.J, Deng, Z, Karplus, P.A, Massey, V.
登録日1998-09-24
公開日1998-09-30
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献On the active site of Old Yellow Enzyme. Role of histidine 191 and asparagine 194.
J.Biol.Chem., 273, 1998
1BWZ
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DIAMINOPIMELATE EPIMERASE FROM HEMOPHILUS INFLUENZAE
分子名称: PROTEIN (DIAMINOPIMELATE EPIMERASE)
著者Cirilli, M, Zheng, R, Scapin, G, Blanchard, J.S.
登録日1998-09-29
公開日1998-12-16
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural symmetry: the three-dimensional structure of Haemophilus influenzae diaminopimelate epimerase.
Biochemistry, 37, 1998
1BXT
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STREPTOCOCCAL SUPERANTIGEN (SSA) FROM STREPTOCOCCUS PYOGENES
分子名称: PROTEIN (STREPTOCOCCAL SUPERANTIGEN)
著者Sundberg, E, Jardetzky, T.
登録日1998-10-08
公開日1998-10-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for HLA-DQ binding by the streptococcal superantigen SSA.
Nat.Struct.Biol., 6, 1999
1BS5
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PEPTIDE DEFORMYLASE AS ZN2+ CONTAINING FORM
分子名称: PROTEIN (PEPTIDE DEFORMYLASE), SULFATE ION, ZINC ION
著者Becker, A, Schlichting, I, Kabsch, W, Groche, D, Schultz, S, Wagner, A.F.V.
登録日1998-09-01
公開日1999-08-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Iron center, substrate recognition and mechanism of peptide deformylase.
Nat.Struct.Biol., 5, 1998
1BSS
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ECORV-T93A/DNA/CA2+
分子名称: 5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', CALCIUM ION, ECORV ENDONUCLEASE
著者Perona, J.J, Horton, N.C.
登録日1998-08-30
公開日1998-09-02
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Metal ion-mediated substrate-assisted catalysis in type II restriction endonucleases
Proc.Natl.Acad.Sci.USA, 95, 1998
1BYA
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CRYSTAL STRUCTURES OF SOYBEAN BETA-AMYLASE REACTED WITH BETA-MALTOSE AND MALTAL: ACTIVE SITE COMPONENTS AND THEIR APPARENT ROLE IN CATALYSIS
分子名称: BETA-AMYLASE, SULFATE ION
著者Mikami, B, Degano, M, Hehre, E.J, Sacchettini, J.C.
登録日1994-01-25
公開日1994-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of soybean beta-amylase reacted with beta-maltose and maltal: active site components and their apparent roles in catalysis.
Biochemistry, 33, 1994
1BYR
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CRYSTAL STRUCTURE OF A PHOSPHOLIPASE D FAMILY MEMBER, NUC FROM SALMONELLA TYPHIMURIUM
分子名称: PROTEIN (ENDONUCLEASE)
著者Stuckey, J.A, Dixon, J.E.
登録日1998-10-19
公開日1999-10-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a phospholipase D family member.
Nat.Struct.Biol., 6, 1999
1BZ7
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FAB FRAGMENT FROM MURINE ASCITES
分子名称: PROTEIN (ANTIBODY R24 (HEAVY CHAIN)), PROTEIN (ANTIBODY R24 (LIGHT CHAIN))
著者Kaminski, M.J, Mackenzie, C.R, Mooibroek, M.J, Dahms, T.E.S, Hirama, T, Houghton, A.N, Chapman, P.B, Evans, S.V.
登録日1998-11-06
公開日1999-11-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains.
J.Biol.Chem., 274, 1999
1BTX
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Episelection: Novel Ki ~Nanomolar Inhibitors of Serine Proteases Selected by Binding or Chemistry on an Enzyme Surface
分子名称: BETA-TRYPSIN, CALCIUM ION, N-(tert-butoxycarbonyl)-L-alanyl-N-[(1S)-5-amino-1-(diethoxyboranyl)pentyl]-L-valinamide
著者Stroud, R.M, Katz, B.A, Finer-Moore, J.
登録日1995-05-17
公開日1995-10-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995
1BZL
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CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH TRYPANOTHIONE, AND THE STRUCTURE-BASED DISCOVERY OF NEW NATURAL PRODUCT INHIBITORS
分子名称: BIS(GAMMA-GLUTAMYL-CYSTEINYL-GLYCINYL)SPERMIDINE, FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE REDUCTASE (OXIDIZED FORM)
著者Bond, C.S, Zhang, Y, Berriman, M, Cunningham, M, Fairlamb, A.H, Hunter, W.N.
登録日1998-11-02
公開日1999-11-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors.
Structure Fold.Des., 7, 1999
1BUA
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BU of 1bua by Molmil
STRUCTURAL AND ENERGETIC ORIGINS OF INDIRECT READOUT IN SITE-SPECIFIC DNA CLEAVAGE BY A RESTRICTION ENDONUCLEASE
分子名称: DNA (5'-D(*AP*AP*AP*GP*AP*CP*IP*TP*CP*TP*T)-3'), ENDONUCLEASE ECORV
著者Perona, J.J, Martin, A.M.
登録日1998-09-03
公開日1998-09-09
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and energetic origins of indirect readout in site-specific DNA cleavage by a restriction endonuclease.
Nat.Struct.Biol., 6, 1999
1BV4
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APO-MANNOSE-BINDING PROTEIN-C
分子名称: PROTEIN (MANNOSE-BINDING PROTEIN-C)
著者Ng, K.K.-S, Weis, W.I.
登録日1998-09-22
公開日1999-01-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Ca2+-dependent structural changes in C-type mannose-binding proteins.
Biochemistry, 37, 1998
1BVO
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DORSAL HOMOLOGUE GAMBIF1 BOUND TO DNA
分子名称: DNA DUPLEX, TRANSCRIPTION FACTOR GAMBIF1
著者Cramer, P, Varrot, A, Barillas-Mury, C, Kafatos, F.C, Mueller, C.W.
登録日1998-09-16
公開日1999-07-12
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA.
Structure Fold.Des., 7, 1999
1BVV
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SUGAR RING DISTORTION IN THE GLYCOSYL-ENZYME INTERMEDIATE OF A FAMILY G/11 XYLANASE
分子名称: ENDO-1,4-BETA-XYLANASE, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol
著者Sidhu, G, Brayer, G.D.
登録日1998-09-18
公開日1999-06-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sugar ring distortion in the glycosyl-enzyme intermediate of a family G/11 xylanase.
Biochemistry, 38, 1999
1BWB
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HIV-1 PROTEASE (V82F/I84V) DOUBLE MUTANT COMPLEXED WITH SD146 OF DUPONT PHARMACEUTICALS
分子名称: PROTEIN (HIV-1 PROTEASE), [4R-(4ALPHA,5ALPHA,6ALPHA,7ALPHA)]-3,3'-{{TETRAHYDRO-5,6-DIHYDROXY-2-OXO-4,7-BIS(PHENYLMETHYL)-1H-1,3-DIAZEPINE-1,3(2H)-DIYL]BIS(METHYLENE)]BIS[N-1H-BENZIMIDAZOL-2-YLBENZAMIDE]
著者Ala, P, Chang, C.H.
登録日1998-09-22
公開日1998-09-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Counteracting HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with XV638 and SD146, cyclic urea amides with broad specificities.
Biochemistry, 37, 1998
1C1T
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RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
分子名称: BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE, CALCIUM ION, MAGNESIUM ION, ...
著者Katz, B.A, Luong, C.
登録日1999-07-21
公開日2000-07-26
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1C2L
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RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
分子名称: CALCIUM ION, CHLORIDE ION, TRYPSIN, ...
著者Katz, B.A, Luong, C.
登録日1999-07-21
公開日2000-07-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1C3F
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Endo-Beta-N-Acetylglucosaminidase H, D130N Mutant
分子名称: ENDO-BETA-N-ACETYLGLUCOSAMINIDASE H
著者Rao, V, Cui, T, Guan, C, Van Roey, P.
登録日1999-07-27
公開日1999-11-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mutations of endo-beta-N-acetylglucosaminidase H active site residues Asp130 and Glu132: activities and conformations.
Protein Sci., 8, 1999
1C3K
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CRYSTAL STRUCTURE OF HELIANTHUS TUBEROSUS LECTIN
分子名称: AGGLUTININ
著者Bourne, Y, Zamboni, V, Barre, A, Peumans, W.J, van Damme, E.J.M, Rouge, P.
登録日1999-07-28
公開日2000-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Helianthus tuberosus lectin reveals a widespread scaffold for mannose-binding lectins.
Structure Fold.Des., 7, 1999
1BWI
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THE 1.8 A STRUCTURE OF MICROBATCH OIL DROP GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
分子名称: PROTEIN (LYSOZYME)
著者Dong, J, Boggon, T.J, Chayen, N.E, Raftery, J, Bi, R.C.
登録日1998-09-24
公開日1998-09-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999

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