PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

---

7QLK	Cis structure intermediate of rsKiiro Illuminated at 200 K 分子名称: GLYCEROL, SULFATE ION, rsKiiro 著者 van Thor, J.J, Baxter, J.M. 登録日 2021-12-20 公開日 2023-07-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.458 Å) 主引用文献 Optical control of ultrafast structural dynamics in a fluorescent protein. Nat.Chem., 15, 2023
7QLI	Cis structure of rsKiiro at 290 K 分子名称: GLYCEROL, SULFATE ION, rsKiiro 著者 van Thor, J.J, Baxter, J.M. 登録日 2021-12-20 公開日 2023-07-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.155 Å) 主引用文献 Optical control of ultrafast structural dynamics in a fluorescent protein. Nat.Chem., 15, 2023
8SLF	Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound) 分子名称: ADENOSINE MONOPHOSPHATE, Glycine--tRNA ligase, MAGNESIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-04-21 公開日 2023-05-03 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound) To be published
4ZGG	Crystal structure of a DJ-1 (PARK7) from Homo sapiens at 1.23 A resolution 分子名称: 1,2-ETHANEDIOL, Protein deglycase DJ-1 著者 Joint Center for Structural Genomics (JCSG), Partnership for Nuclear Receptor Signaling Code Biology (NHRS), Partnership for T-Cell Biology (TCELL) 登録日 2015-04-22 公開日 2015-05-20 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Crystal structure of a DJ-1 (PARK7) from Homo sapiens at 1.23 A resolution To be published
4QIR	Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-2-(pyridin-3-yl)ethylGlyP[CH2]Phe 分子名称: 3-{[(R)-1-amino-3-(pyridin-3-yl)propyl](hydroxy)phosphoryl}-(S)-2-benzylpropanoic acid, Aminopeptidase N, GLYCEROL, ... 著者 Nocek, B, Joachimiak, A, Berlicki, L, Vassiliou, S, Mucha, A. 登録日 2014-06-01 公開日 2014-09-24 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J.Med.Chem., 57, 2014
7SCF	M. tb EgtD in complex with HD2 分子名称: (2S)-3-(1H-imidazol-5-yl)-2-(1H-pyrrol-1-yl)propanoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Sudasinghe, T.D, Ronning, D.R. 登録日 2021-09-28 公開日 2021-12-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Inhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production. Sci Rep, 11, 2021
6CCH	NMR data-driven model of GTPase KRas-GMPPNP tethered to a nanodisc (E3 state) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... 著者 Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. 登録日 2018-02-07 公開日 2018-08-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25, 2018
4QK2	Structural and Catalytic Effects of Proline Substitution and Surface Loop Deletion in the Extended Active Site of Human Carbonic Anhydrase II - E234P 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION 著者 Boone, C.D, Rasi, V, McKenna, R. 登録日 2014-06-05 公開日 2015-03-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.519 Å) 主引用文献 Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase II. Febs J., 282, 2015
6U90	Crystal structure of DNMT3B(N779A)-DNMT3L in complex with CpGpT DNA 分子名称: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Gao, L, Song, J. 登録日 2019-09-06 公開日 2020-06-10 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (3.00081754 Å) 主引用文献 Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms To Be Published
2B1V	Human estrogen receptor alpha ligand-binding domain in complex with OBCP-1M and a glucocorticoid receptor interacting protein 1 NR box II peptide 分子名称: 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, Estrogen receptor, Nuclear receptor coactivator 2 著者 Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L. 登録日 2005-09-16 公開日 2006-05-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J.Biol.Chem., 281, 2006
8SLD	Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (Apo) 分子名称: Glycine--tRNA ligase, MAGNESIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-04-21 公開日 2023-05-03 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (Apo) To be published
6UD3	Full length Glycine receptor reconstituted in lipid nanodisc in Gly/PTX-bound open/blocked conformation 分子名称: (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ... 著者 Kumar, A, Basak, S, Chakrapani, S. 登録日 2019-09-18 公開日 2020-07-29 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs. Nat Commun, 11, 2020
8SLG	Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (glycyl adenylate bound) 分子名称: 5'-O-(glycylsulfamoyl)adenosine, GLYCEROL, Glycine--tRNA ligase, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-04-21 公開日 2023-05-03 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (glycyl adenylate bound) To be published
4PXX	Crystal structure of a highly thermal stabilized variant of Human Carbonic Anhydrase II 分子名称: CHOLIC ACID, Carbonic anhydrase 2, MAGNESIUM ION, ... 著者 Boone, C.D, Habibzadegan, A, McKenna, R. 登録日 2014-03-25 公開日 2015-06-10 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Crystal structure of a highly thermal stabilized variant of Human Carbonic Anhydrase II TO BE PUBLISHED
6D6H	Triclinic lysozyme cryocooled to 100 K with 47% MPD as cryoprotectant 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Lysozyme C, NITRATE ION 著者 Juers, D.H. 登録日 2018-04-20 公開日 2018-09-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.000064 Å) 主引用文献 The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
6UKT	Cryo-EM structure of mammalian Ric-8A:Galpha(i):nanobody complex 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, NB8109, NB8117, ... 著者 Mou, T.C, Zhang, K, Johnston, J.D, Chiu, W, Sprang, S.R. 登録日 2019-10-05 公開日 2020-03-11 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.87 Å) 主引用文献 Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to G alpha i1. Nat Commun, 11, 2020
8SLH	Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound, hexagonal form) 分子名称: ADENOSINE MONOPHOSPHATE, Glycine--tRNA ligase, MAGNESIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-04-21 公開日 2023-05-03 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound, hexagonal form) To be published
6D9G	X-ray Structure of the FAB Fragment of 15B8, a Murine Monoclonal Antibody Specific for the Human Serotonin Transporter 分子名称: Antibody heavy chain Fab, Antibody light chain Fab 著者 Coleman, J.A, Yang, D, Gouaux, E. 登録日 2018-04-29 公開日 2019-04-24 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport. Nature, 569, 2019
6D9Z	Structure of CysZ, a sulfate permease from Pseudomonas Denitrificans 分子名称: Sulfate transporter CysZ, octyl beta-D-glucopyranoside 著者 Sanghai, Z.A, Clarke, O.B, Liu, Q, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Mancia, F. 登録日 2018-04-30 公開日 2018-05-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.4021318 Å) 主引用文献 Structure-based analysis of CysZ-mediated cellular uptake of sulfate. Elife, 7, 2018
4ZMC	Crystal structure of the PmFTN variant E130A soaked in iron (5 min) 分子名称: FE (III) ION, Ferritin 著者 Pfaffen, S, Murphy, M.E.P. 登録日 2015-05-02 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Diatom Ferritin Optimized for Iron Oxidation but Not Iron Storage. J.Biol.Chem., 290, 2015
7T3P	IP3 and ATP bound type 3 IP3 receptor in the pre-active A state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... 著者 Schmitz, E.A, Takahashi, H, Karakas, E. 登録日 2021-12-08 公開日 2022-03-23 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
6DA1	ETS1 in complex with synthetic SRR mimic 分子名称: Protein C-ets-1, SULFATE ION, serine-rich region (SRR) peptide 著者 Perez-Borrajero, C, Okon, M, Lin, C.S, Scheu, K, Murphy, M.E.P, Graves, B.J, McIntosh, L.P. 登録日 2018-05-01 公開日 2019-01-16 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.000127 Å) 主引用文献 The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. J. Mol. Biol., 431, 2019
7T3Q	IP3 and ATP bound type 3 IP3 receptor in the pre-active B state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... 著者 Schmitz, E.A, Takahashi, H, Karakas, E. 登録日 2021-12-08 公開日 2022-03-23 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
4IFC	Crystal Structure of ADP-bound Human PRPF4B kinase domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog 著者 Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L. 登録日 2012-12-14 公開日 2013-08-28 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches. J.Biol.Chem., 288, 2013
6TY6	Variant W229D/F290W-2 of the last common ancestor of Gram-negative bacteria beta-lactamase class A (GNCA4) bound to 5(6)-nitrobenzotriazole (TS-analog) 分子名称: 6-NITROBENZOTRIAZOLE, ACETATE ION, Beta lactamase (GNCA4-2), ... 著者 Gavira, J.A, Risso, V, Sanchez-Ruiz, J.M, Romero-Rivera, A, Kamerlin, S.C.L, Ortega-Munoz, M, Santoyo-Gonzalez, F. 登録日 2020-01-15 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Enhancing ade novoenzyme activity by computationally-focused ultra-low-throughput screening. Chem Sci, 11, 2020

<1045104610471048104910501051105210531054105510561057105810591060>