6U90

Crystal structure of DNMT3B(N779A)-DNMT3L in complex with CpGpT DNA

Summary for 6U90

Entry DOI	10.2210/pdb6u90/pdb
Descriptor	DNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5)-methyltransferase 3-like, CpGpT DNA (25-MER), ... (6 entities in total)
Functional Keywords	dnmt3b, dnmt3l, dna methylation, methyltransferase, transferase-dna complex, transferase, transferase/dna
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	130965.14
Authors	Gao, L.,Song, J. (deposition date: 2019-09-06, release date: 2020-06-10, Last modification date: 2023-10-11)
Primary citation	Gao, L. Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms To Be Published,
Experimental method	X-RAY DIFFRACTION (3.00081756367 Å)

Structure validation