6U90
Crystal structure of DNMT3B(N779A)-DNMT3L in complex with CpGpT DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | DNA (cytosine-5)-methyltransferase 3B | polymer | 291 | 33143.4 | 2 | UniProt (Q9UBC3) Pfam (PF00145) | Homo sapiens (Human) | Dnmt3b,DNA methyltransferase HsaIIIB,M.HsaIIIB |
| 2 | B, C (B, C) | DNA (cytosine-5)-methyltransferase 3-like | polymer | 209 | 24163.7 | 2 | UniProt (Q9UJW3) | Homo sapiens (Human) | |
| 3 | E, F (E, F) | CpGpT DNA (25-MER) | polymer | 25 | 7699.0 | 2 | Homo sapiens | ||
| 4 | G, I (A, D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | H, J (A, D) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 6 | K, L, M, N (A, B, D, E) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
A, D: 563 - 853 (UniProt: Q9UBC3)
| PDB | External Database | Details |
|---|---|---|
| Ala 779 | Asn 779 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 130012.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 953.0 | |
| All* | Total formula weight | 130965.1 |
