3A4W
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![BU of 3a4w by Molmil](/molmil-images/mine/3a4w) | Crystal structures of catalytic site mutants of active domain 2 of thermostable chitinase from Pyrococcus furiosus complexed with chito-oligosaccharides | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase, MAGNESIUM ION, ... | 著者 | Tsuji, H, Nishimura, S, Inui, T, Ishikawa, K, Nakamura, T, Uegaki, K. | 登録日 | 2009-07-22 | 公開日 | 2010-06-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus- the role of conserved residues in the active site Febs J., 277, 2010
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8T32
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![BU of 8t32 by Molmil](/molmil-images/mine/8t32) | Crystal structure of K48 acetylated GABARAP in complex with the LIR of TP53INP2/DOR | 分子名称: | Gamma-aminobutyric acid receptor-associated protein, LIR of DOR, TRIETHYLENE GLYCOL | 著者 | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | 登録日 | 2023-06-07 | 公開日 | 2024-05-22 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.051 Å) | 主引用文献 | Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy, 2024
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7KAD
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![BU of 7kad by Molmil](/molmil-images/mine/7kad) | Co-crystal structure of alpha glucosidase with compound 6 | 分子名称: | (1S,2S,3R,4S,5S)-1-(hydroxymethyl)-5-[(6-{[2-nitro-4-(1H-1,2,3-triazol-1-yl)phenyl]amino}hexyl)amino]cyclohexane-1,2,3,4-tetrol, 1,2-ETHANEDIOL, CALCIUM ION, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2020-09-30 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | 主引用文献 | N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity. J.Med.Chem., 64, 2021
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7KB8
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![BU of 7kb8 by Molmil](/molmil-images/mine/7kb8) | Co-crystal structure of alpha glucosidase with compound 8 | 分子名称: | (1S,2S,3R,4S,5S)-1-(hydroxymethyl)-5-[(4-{[2-nitro-4-(triazan-1-yl)phenyl]amino}butyl)amino]cyclohexane-1,2,3,4-tetrol, 1,2-ETHANEDIOL, CALCIUM ION, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2020-10-01 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.385 Å) | 主引用文献 | N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity. J.Med.Chem., 64, 2021
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4M94
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2DG5
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![BU of 2dg5 by Molmil](/molmil-images/mine/2dg5) | Crystal Structure of Gamma-glutamyl transpeptidase from Escherichia coli in complex with hydrolyzed Glutathione | 分子名称: | CALCIUM ION, GLUTAMIC ACID, GLYCEROL, ... | 著者 | Okada, T, Wada, K, Fukuyama, K. | 登録日 | 2006-03-08 | 公開日 | 2006-04-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structures of gamma-glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate. Proc.Natl.Acad.Sci.Usa, 103, 2006
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7Q1X
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![BU of 7q1x by Molmil](/molmil-images/mine/7q1x) | Acetyltrasferase(3) type IIIa in complex with neomycin B | 分子名称: | Aminoglycoside N(3)-acetyltransferase III, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Pontillo, N, Guskov, A. | 登録日 | 2021-10-21 | 公開日 | 2022-11-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism To Be Published
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7PTH
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4M9H
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![BU of 4m9h by Molmil](/molmil-images/mine/4m9h) | DNA Polymerase Beta E295K Soaked with dTTP | 分子名称: | CHLORIDE ION, DNA Downstream Strand, DNA Primer Strand, ... | 著者 | Eckenroth, B.E, Doublie, S. | 登録日 | 2013-08-14 | 公開日 | 2013-10-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.394 Å) | 主引用文献 | The E295K Cancer Variant of Human Polymerase beta Favors the Mismatch Conformational Pathway during Nucleotide Selection. J.Biol.Chem., 288, 2013
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3EWS
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![BU of 3ews by Molmil](/molmil-images/mine/3ews) | Human DEAD-box RNA-helicase DDX19 in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B | 著者 | Lehtio, l, Karlberg, t, Andersson, j, Arrowsmith, c.h, Berglund, h, Bountra, c, Collins, r, Dahlgren, l.g, Edwards, a.m, Flodin, s, Flores, a, Graslund, s, Hammarstrom, m, Johansson, a, Johansson, i, Kotenyova, t, Moche, m, Nilsson, m.e, Nordlund, p, Nyman, t, Olesen, k, Persson, c, Sagemark, j, Thorsell, a.g, Tresaugues, l, Van den berg, s, Weigelt, j, Welin, m, Wikstrom, m, Wisniewska, m, Schueler, h, Structural Genomics Consortium (SGC) | 登録日 | 2008-10-16 | 公開日 | 2008-11-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch. J.Biol.Chem., 284, 2009
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7JTY
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![BU of 7jty by Molmil](/molmil-images/mine/7jty) | Co-crystal structure of alpha glucosidase with compound 1 | 分子名称: | (1S,2S,3R,4S,5S)-5-(butylamino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, 1,2-ETHANEDIOL, Alpha glucosidase 2 alpha neutral subunit, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2020-08-18 | 公開日 | 2021-10-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity. J.Med.Chem., 64, 2021
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3AB2
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![BU of 3ab2 by Molmil](/molmil-images/mine/3ab2) | Crystal structure of aspartate kinase from Corynebacterium glutamicum in complex with threonine | 分子名称: | Aspartokinase, THREONINE | 著者 | Yoshida, A, Tomita, T, Kuzuyama, T, Nishiyama, M. | 登録日 | 2009-11-30 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum J.Biol.Chem., 285, 2010
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7Q0Q
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7PR9
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![BU of 7pr9 by Molmil](/molmil-images/mine/7pr9) | Crystal structure of Burkholderia pseudomallei heparanase in complex with covalent inhibitor VL166 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-(2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, Glyco_hydro_44 domain-containing protein | 著者 | Wu, L, Armstrong, Z, Davies, G.J. | 登録日 | 2021-09-21 | 公開日 | 2022-08-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
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3F41
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![BU of 3f41 by Molmil](/molmil-images/mine/3f41) | Structure of the tandemly repeated protein tyrosine phosphatase like phytase from Mitsuokella multacida | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, Phytase | 著者 | Gruninger, R.J, Selinger, L.B, Mosimann, S.C. | 登録日 | 2008-10-31 | 公開日 | 2009-06-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural analysis of a multifunctional, tandemly repeated inositol polyphosphatase. J.Mol.Biol., 392, 2009
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4LT4
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![BU of 4lt4 by Molmil](/molmil-images/mine/4lt4) | Crystal structure of arginine inhibited Ribosome inactivating protein from Momordica balsamina at 1.69 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ARGININE, GLYCEROL, ... | 著者 | Yamini, S, Pandey, S, Bhushan, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2013-07-23 | 公開日 | 2013-08-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Crystal structure of arginine inhibited Ribosome inactivating protein from Momordica balsamina at 1.69 A resolution To be Published
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8THC
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![BU of 8thc by Molmil](/molmil-images/mine/8thc) | Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to a cracked PCNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ELG1 isoform 1, MAGNESIUM ION, ... | 著者 | Zheng, F, Yao, Y.N, Georgescu, R, O'Donnell, M.E, Li, H. | 登録日 | 2023-07-14 | 公開日 | 2024-05-22 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Structure of the PCNA unloader Elg1-RFC. Sci Adv, 10, 2024
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2DJF
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![BU of 2djf by Molmil](/molmil-images/mine/2djf) | Crystal Structure of human dipeptidyl peptidase I (Cathepsin C) in complex with the inhibitor Gly-Phe-CHN2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CHLORIDE ION, ... | 著者 | Molgaard, A, Arnau, J, Lauritzen, C, Larsen, S, Petersen, G, Pedersen, J. | 登録日 | 2006-04-02 | 公開日 | 2006-11-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of human dipeptidyl peptidase I (cathepsin C) in complex with the inhibitor Gly-Phe-CHN2 Biochem.J., 401, 2007
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4LTE
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![BU of 4lte by Molmil](/molmil-images/mine/4lte) | Structure of Cysteine-free Human Insulin Degrading Enzyme in Complex with Macrocyclic Inhibitor | 分子名称: | 2,6-DIAMINO-HEXANOIC ACID AMIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FUMARIC ACID, ... | 著者 | Foda, Z.H, Seeliger, M.A, Saghatelian, A, Liu, D.R. | 登録日 | 2013-07-23 | 公開日 | 2014-05-21 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.705 Å) | 主引用文献 | Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones. Nature, 511, 2014
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8TBY
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![BU of 8tby by Molmil](/molmil-images/mine/8tby) | Apo Bcs1, unsymmetrized | 分子名称: | Mitochondrial chaperone BCS1 | 著者 | Zhan, J, Xia, D. | 登録日 | 2023-06-29 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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3EYX
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![BU of 3eyx by Molmil](/molmil-images/mine/3eyx) | Crystal structure of Carbonic Anhydrase Nce103 from Saccharomyces cerevisiae | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Carbonic anhydrase, ... | 著者 | Teng, Y.B, Jiang, Y.L, Chen, Y, Zhou, C.Z. | 登録日 | 2008-10-22 | 公開日 | 2009-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structural insights into the substrate tunnel of Saccharomyces cerevisiae carbonic anhydrase Nce103. Bmc Struct.Biol., 9, 2009
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4LUG
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5EWI
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7K59
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![BU of 7k59 by Molmil](/molmil-images/mine/7k59) | Structure of apo VCP hexamer generated from bacterially recombinant VCP/p97 | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | 登録日 | 2020-09-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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5EWY
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![BU of 5ewy by Molmil](/molmil-images/mine/5ewy) | Scabin toxin from Streptomyces Scabies in complex with inhibitor P6E | 分子名称: | 4-(8-fluoranyl-6-oxidanylidene-1,3,4,5-tetrahydrobenzo[c][1,6]naphthyridin-2-yl)butanoic acid, Putative ADP-Ribosyltransferase Scabin | 著者 | Ravulapalli, R, Lyons, B, Merrill, A.R. | 登録日 | 2015-11-22 | 公開日 | 2016-03-23 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Scabin, a Novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies. J.Biol.Chem., 291, 2016
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