7Q1X
Acetyltrasferase(3) type IIIa in complex with neomycin B
Summary for 7Q1X
Entry DOI | 10.2210/pdb7q1x/pdb |
Related | 7q0q 7q10 7q1d |
Descriptor | Aminoglycoside N(3)-acetyltransferase III, GLYCEROL, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | acetyltrasferase, aminoglycosides, inhibitor, complex, antibiotic |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 64593.85 |
Authors | Pontillo, N.,Guskov, A. (deposition date: 2021-10-21, release date: 2022-11-02, Last modification date: 2024-01-31) |
Primary citation | Pontillo, N.,Warszawik, E.M.,Partipilo, M.,Stetsenko, A.,Loznik, M.,Yang, X.,Slotboom, D.J.,Guskov, A.,Herrmann, A. The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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