7Q1X

Acetyltrasferase(3) type IIIa in complex with neomycin B

Summary for 7Q1X

Entry DOI	10.2210/pdb7q1x/pdb
Related	7q0q 7q10 7q1d
Descriptor	Aminoglycoside N(3)-acetyltransferase III, GLYCEROL, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
Functional Keywords	acetyltrasferase, aminoglycosides, inhibitor, complex, antibiotic
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	2
Total formula weight	64593.85
Authors	Pontillo, N.,Guskov, A. (deposition date: 2021-10-21, release date: 2022-11-02, Last modification date: 2024-01-31)
Primary citation	Pontillo, N.,Warszawik, E.M.,Partipilo, M.,Stetsenko, A.,Loznik, M.,Yang, X.,Slotboom, D.J.,Guskov, A.,Herrmann, A. The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism To Be Published,
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation