7Q1X

Acetyltrasferase(3) type IIIa in complex with neomycin B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008080	molecular_function	N-acetyltransferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016999	biological_process	antibiotic metabolic process
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
A	0046356	biological_process	acetyl-CoA catabolic process
A	0046677	biological_process	response to antibiotic
A	0071236	biological_process	cellular response to antibiotic
A	0120225	molecular_function	coenzyme A binding
A	1901742	biological_process	2-deoxystreptamine metabolic process
B	0008080	molecular_function	N-acetyltransferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016999	biological_process	antibiotic metabolic process
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
B	0046356	biological_process	acetyl-CoA catabolic process
B	0046677	biological_process	response to antibiotic
B	0071236	biological_process	cellular response to antibiotic
B	0120225	molecular_function	coenzyme A binding
B	1901742	biological_process	2-deoxystreptamine metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQK, ECO:0007744|PDB:7MQL, ECO:0007744|PDB:7MQM

Chain	Residue	Details
A	HIS51
A	GLU143
A	TYR166
A	THR193
A	HIS196
A	THR232
A	PHE241
B	HIS51
B	ALA52
B	SER53
B	VAL54
A	ALA52
B	LYS55
B	TYR84
B	SER124
B	VAL125
B	PHE129
B	GLU143
B	TYR166
B	THR193
B	HIS196
B	THR232
A	SER53
B	PHE241
A	VAL54
A	LYS55
A	TYR84
A	SER124
A	VAL125
A	PHE129

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQK, ECO:0007744|PDB:7MQM

Chain	Residue	Details
A	ASP92
A	THR191
B	ASP92
B	THR191

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQL, ECO:0007744|PDB:7MQM

Chain	Residue	Details
A	GLU122
A	ASP190
B	GLU122
B	ASP190

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site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:35921328, ECO:0007744|PDB:7MQL

Chain	Residue	Details
A	GLY233
B	GLY233

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