3EWS

Human DEAD-box RNA-helicase DDX19 in complex with ADP

Summary for 3EWS

• Entry DOI: 10.2210/pdb3ews/pdb
• Descriptor: ATP-dependent RNA helicase DDX19B, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: rna helicase, dead, adp, structural genomics, structural genomics consortium, sgc, rrna, atp-binding, hydrolase, nucleotide-binding, rna-binding, mrna, alternative splicing, cytoplasm, helicase, membrane, mrna transport, nuclear pore complex, nucleus, protein transport, translocation, transport
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: Q9UMR2
• Total number of polymer chains: 2
• Total formula weight: 101848.22

Authors

Lehtio, l.,Karlberg, t.,Andersson, j.,Arrowsmith, c.h.,Berglund, h.,Bountra, c.,Collins, r.,Dahlgren, l.g.,Edwards, a.m.,Flodin, s.,Flores, a.,Graslund, s.,Hammarstrom, m.,Johansson, a.,Johansson, i.,Kotenyova, t.,Moche, m.,Nilsson, m.e.,Nordlund, p.,Nyman, t.,Olesen, k.,Persson, c.,Sagemark, j.,Thorsell, a.g.,Tresaugues, l.,Van den berg, s.,Weigelt, j.,Welin, m.,Wikstrom, m.,Wisniewska, m.,Schueler, h.,Structural Genomics Consortium (SGC) (deposition date: 2008-10-16, release date: 2008-11-04, Last modification date: 2023-12-27)

• Primary citation: Collins, R.,Karlberg, T.,Lehtio, L.,Schutz, P.,van den Berg, S.,Dahlgren, L.G.,Hammarstrom, M.,Weigelt, J.,Schuler, H.; The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch.; J.Biol.Chem., 284:10296-10300, 2009; PubMed: 19244245; DOI: 10.1074/jbc.C900018200

Experimental method

X-RAY DIFFRACTION (2.7 Å)