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6G6S
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Crystal structure of human Acinus RNA recognition motif domain
分子名称: Apoptotic chromatin condensation inducer in the nucleus
著者Fernandes, H, Czapinska, H, Grudziaz, K, Bujnicki, J.M, Nowacka, M.
登録日2018-04-03
公開日2018-06-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of human Acinus RNA recognition motif domain.
PeerJ, 6, 2018
6G3C
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Crystal Structure of JAK2-V617F pseudokinase domain in complex with Compound 2
分子名称: 1,2-ETHANEDIOL, 2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7,7-trimethyl-8-(3-methylbutyl)pteridin-6-one, Tyrosine-protein kinase
著者Dekker, C, Hinniger, A.
登録日2018-03-24
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery and Structural Characterization of ATP-Site Ligands for the Wild-Type and V617F Mutant JAK2 Pseudokinase Domain.
Acs Chem.Biol., 14, 2019
5LYB
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BU of 5lyb by Molmil
Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCPmn
分子名称: 18S rRNA, 25S rRNA, 40S Ribosomal Protein S12, ...
著者Melnikov, S, Mailliot, J.
登録日2016-09-26
公開日2016-11-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
1DHK
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STRUCTURE OF PORCINE PANCREATIC ALPHA-AMYLASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BEAN LECTIN-LIKE INHIBITOR, ...
著者Bompard-Gilles, C, Payan, F.
登録日1996-10-14
公開日1997-12-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Substrate mimicry in the active center of a mammalian alpha-amylase: structural analysis of an enzyme-inhibitor complex.
Structure, 4, 1996
6G6U
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The dynamic nature of the VDAC1 channels in bilayers: human VDAC1 at 2.7 Angstrom resolution
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, NITRATE ION, Voltage-dependent anion-selective channel protein 1
著者Razeto, A, Gribbon, P, Loew, C.
登録日2018-04-03
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献The dynamic nature of the VDAC1 channels in bilayers as revealed by two crystal structures of the human isoform in bicelles at 2.7 and 3.3 Angstrom resolution: implications for VDAC1 voltage-dependent mechanism and for its oligomerization
To Be Published
6G75
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Crystal structure of the common ancestor of haloalkane dehalogenases and Renilla luciferase (AncHLD-RLuc)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Common ancestor of haloalkane dehalogenase and Renilla luciferase (AncHLD-RLuc), ...
著者Chaloupkova, R, Waterman, J, Marek, M, Damborsky, J.
登録日2018-04-04
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.391 Å)
主引用文献Light-Emitting Dehalogenases: Reconstruction of Multifunctional Biocatalysts
Acs Catalysis, 2019
1DMB
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REFINED 1.8 ANGSTROMS STRUCTURE REVEALS THE MECHANISM OF BINDING OF A CYCLIC SUGAR, BETA-CYCLODEXTRIN, TO THE MALTODEXTRIN BINDING PROTEIN
分子名称: Cycloheptakis-(1-4)-(alpha-D-glucopyranose), D-MALTODEXTRIN BINDING PROTEIN
著者Sharff, A.J, Quiocho, F.A.
登録日1993-06-10
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Refined 1.8-A structure reveals the mode of binding of beta-cyclodextrin to the maltodextrin binding protein.
Biochemistry, 32, 1993
6KKJ
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Crystal structure of Drug:Proton Antiporter-1 (DHA1) Family SotB, in the inward open conformation
分子名称: Sugar efflux transporter, nonyl beta-D-glucopyranoside
著者Xiao, Q.J, Deng, D.
登録日2019-07-25
公開日2020-07-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.385 Å)
主引用文献Visualizing the nonlinear changes of a drug-proton antiporter from inward-open to occluded state.
Biochem.Biophys.Res.Commun., 534, 2021
7U6E
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BU of 7u6e by Molmil
Head region of insulin receptor ectodomain (A-isoform) bound to the non-insulin agonist IM462
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IM462, ...
著者Kirk, N.S, Lawrence, M.C.
登録日2022-03-03
公開日2022-10-05
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Activation of the human insulin receptor by non-insulin-related peptides
Nat Commun, 13, 2022
5A71
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Open and closed conformations and protonation states of Candida antarctica Lipase B: atomic resolution native
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ISOPROPYL ALCOHOL, LIPASE B, ...
著者Stauch, B, Fisher, S.J, Cianci, M.
登録日2015-07-02
公開日2015-10-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (0.91 Å)
主引用文献Open and Closed States of Candida Antarctica Lipase B: Protonation and the Mechanism of Interfacial Activation.
J.Lipid Res., 56, 2015
5A8Q
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Crystal structure beta-glucanase SdGluc5_26A from Saccharophagus degradans in complex with tetrasaccharide A obtained by soaking
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Sulzenbacher, G, Lafond, M, Freyd, T, Henrissat, B, Coutinho, R.M, Berrin, J.G, Garron, M.L.
登録日2015-07-16
公開日2016-01-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Quaternary Structure of a Glycoside Hydrolase Dictates Specificity Towards Beta-Glucans
J.Biol.Chem., 291, 2016
1DN2
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FC FRAGMENT OF HUMAN IGG1 IN COMPLEX WITH AN ENGINEERED 13 RESIDUE PEPTIDE DCAWHLGELVWCT-NH2
分子名称: ENGINEERED PEPTIDE, IMMUNOGLOBULIN LAMBDA HEAVY CHAIN, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者DeLano, W.L, Ultsch, M.H, de Vos, A.M, Wells, J.A.
登録日1999-12-15
公開日2000-05-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Convergent solutions to binding at a protein-protein interface.
Science, 287, 2000
1DP4
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DIMERIZED HORMONE BINDING DOMAIN OF THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATRIAL NATRIURETIC PEPTIDE RECEPTOR A, ...
著者van den Akker, F, Zhang, X, Miyagi, M, Huo, X, Misono, K.S, Yee, V.C.
登録日1999-12-23
公開日2000-07-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the dimerized hormone-binding domain of a guanylyl-cyclase-coupled receptor.
Nature, 406, 2000
8CZJ
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A bacteria Zrt/Irt-like protein in the apo state
分子名称: Putative membrane protein, SULFATE ION, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate
著者Zhang, Y, Hu, J.
登録日2022-05-24
公開日2023-02-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter.
Nat Commun, 14, 2023
7W62
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Mevo lectin complex with mannotetraose (Man4)
分子名称: 1,2-ETHANEDIOL, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, ...
著者Sivaji, N, Vijayan, M.
登録日2021-12-01
公開日2023-01-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mevo lectin complex with mannotetraose (Man4)
To Be Published
7FBJ
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Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing nanobody 17F6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, New antigen receptor variable domain, ...
著者Zhu, J, Xu, T, Feng, B, Liu, J.
登録日2021-07-11
公開日2022-07-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape.
Small Methods, 6, 2022
7WL5
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BU of 7wl5 by Molmil
Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Equine/Guangxi/25/2010(H5N1) and A/Equine/Guangxi/68/2010(H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Wei, X, Yang, X, Chen, Q, Meng, G.
登録日2022-01-12
公開日2023-01-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Equine/Guangxi/25/2010(H5N1) and A/Equine/Guangxi/68/2010(H5N1)
To Be Published
7WQV
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Crystal structure of a neutralizing monoclonal antibody (Ab08) in complex with SARS-CoV-2 receptor-binding domain (RBD)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab08, ...
著者Zha, J, Meng, L, Zhang, X, Li, D.
登録日2022-01-26
公開日2023-01-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy.
Plos Pathog., 19, 2023
7FBK
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Crystal structure of SARS-CoV-2 receptor binding domain N501Y mutant in complex with neutralizing nanobody 20G6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, New antigen receptor variable domain, Spike protein S1
著者Zhu, J, Xu, T, Feng, B, Liu, J.
登録日2021-07-11
公開日2022-07-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape.
Small Methods, 6, 2022
3DL9
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Crystal structure of CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2
分子名称: (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3-diol, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Cytochrome P450 2R1, ...
著者Strushkevich, N.V, Tempel, W, Gilep, A.A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2008-06-26
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.721 Å)
主引用文献Crystal structure of CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2.
To be Published
7LWS
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UK (B.1.1.7) SARS-CoV-2 S-GSAS-D614G variant spike protein in the 3-RBD-down conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-01
公開日2021-03-31
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation and antigenicity.
Biorxiv, 2021
7WR9
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Local CryoEM structure of the SARS-CoV S2P in complex with BD55-3152 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BD55-3152H, BD55-3152L, ...
著者Du, S, Xiao, J.Y.
登録日2022-01-26
公開日2023-02-01
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Local CryoEM structure of the SARS-CoV S2P in complex with BD55-3152 Fab
To Be Published
8D3Z
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Crystal structure of GalS1 in complex with Manganese from Populus trichocarpas
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Galactan synthase, ...
著者Pereira, J.H, Prabhakar, P.K, Urbanowicz, B.R, Adams, P.D.
登録日2022-06-01
公開日2023-03-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structural and biochemical insight into a modular beta-1,4-galactan synthase in plants.
Nat.Plants, 9, 2023
6HFA
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Crystal structure of hDM2 in complex with a C-terminal triurea capped peptide chimera foldamer.
分子名称: E3 ubiquitin-protein ligase Mdm2, LM266, 1-[(2~{S})-2-azanyl-3-methyl-butyl]urea
著者Buratto, J, Mauran, L, Goudreau, S, Fribourg, S, Guichard, G.
登録日2018-08-21
公開日2020-07-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Basis for alpha-Helix Mimicry and Inhibition of Protein-Protein Interactions with Oligourea Foldamers.
Angew.Chem.Int.Ed.Engl., 2020
5BK3
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Crystal structure of the neutralizing anti-circumsporozoite protein 580 antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 580 Antibody, heavy chain, ...
著者Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P.
登録日2017-09-12
公開日2017-12-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017

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