PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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7V0P	Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a potently neutralizing human antibody IgG-106 分子名称: IgG 106 Fab heavy chain, IgG 106 Fab light chain, Spike glycoprotein E1, ... 著者 Bandyopadhyay, A, Klose, T, Kuhn, R.J. 登録日 2022-05-10 公開日 2023-04-05 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 120, 2023
7TGF	Single-domain VHH intrabodies neutralize ricin toxin. 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ricin chain A, ... 著者 Rudolph, M.J, Mantis, N. 登録日 2022-01-07 公開日 2022-10-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.347 Å) 主引用文献 Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins. J.Biol.Chem., 298, 2022
7K22	Murine polyomavirus pentavalent capsomer with 8A7H5 Fab, subparticle reconstruction 分子名称: 8A7H5 Fab heavy chain, 8A7H5 Fab light chain, Capsid protein VP1 著者 Goetschius, D.J, Hafenstein, S.L. 登録日 2020-09-08 公開日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Antibody escape by polyomavirus capsid mutation facilitates neurovirulence. Elife, 9, 2020
7K23	Murine polyomavirus hexavalent capsomer with 8A7H5 Fab, subparticle reconstruction 分子名称: 8A7H5 Fab heavy chain, 8A7H5 Fab light chain, Capsid protein VP1 著者 Goetschius, D.J, Hafenstein, S.L. 登録日 2020-09-08 公開日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Antibody escape by polyomavirus capsid mutation facilitates neurovirulence. Elife, 9, 2020
7K25	Murine polyomavirus hexavalent capsomer, subparticle reconstruction 分子名称: Capsid protein VP1 著者 Goetschius, D.J, Hafenstein, S.L. 登録日 2020-09-08 公開日 2020-10-07 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Antibody escape by polyomavirus capsid mutation facilitates neurovirulence. Elife, 9, 2020
7K24	Murine polyomavirus pentavalent capsomer, subparticle reconstruction 分子名称: Capsid protein VP1 著者 Goetschius, D.J, Hafenstein, S.L. 登録日 2020-09-08 公開日 2020-10-07 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Antibody escape by polyomavirus capsid mutation facilitates neurovirulence. Elife, 9, 2020
7MXE	Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ... 著者 Abernathy, M.E, Bjorkman, P.J. 登録日 2021-05-19 公開日 2021-10-27 最終更新日 2021-11-03 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope. Npj Vaccines, 6, 2021
5J57	V5E1-RTA complex 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ricin, ... 著者 Rudolph, M.J. 登録日 2016-04-01 公開日 2016-12-07 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J. Biol. Chem., 292, 2017
7ZWF	Pfs48/45 bound to scFv fragment of monoclonal antibody 32F3 分子名称: 32F3scFv, Gametocyte surface protein P45/48, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Ko, K.T, Lennartz, F.L, Higgins, M.K. 登録日 2022-05-19 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.132 Å) 主引用文献 Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies. Nat Commun, 13, 2022
8E1G	SARS-CoV-2 RBD in complex with Omicron-neutralizing antibody 2A10 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2A10 Fab, heavy chain, ... 著者 Wasserman, H, Hastie, K.M, Buck, T.K, Saphire, E.O. 登録日 2022-08-10 公開日 2023-06-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence. Cell Rep, 42, 2023
5TP3	Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4 分子名称: F-VHH-4 著者 Wrapp, D, Gilman, M.S.A, McLellan, J.S. 登録日 2016-10-19 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.874 Å) 主引用文献 Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017
6CDE	Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ... 著者 Acharya, P, Xu, K, Liu, K, Carragher, B, Potter, C.S, Kwong, P.D. 登録日 2018-02-08 公開日 2018-05-16 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nat. Med., 24, 2018
7D3L	FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY F145 分子名称: F145 VH, F145 VL, O/TIBET/99 VP1, ... 著者 He, Y, Lou, Z. 登録日 2020-09-19 公開日 2021-04-14 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization. Plos Pathog., 17, 2021
6XRJ	Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage 分子名称: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment 著者 Manne, K, Nicely, N.I, Acharya, P. 登録日 2020-07-13 公開日 2020-12-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
5E1H	Ricin toxin in complex with neutralizing single chain monoclonal antibodies (VHHs) 分子名称: CHLORIDE ION, F8(JOB10) VHH antibody, Ricin 著者 Rudolph, M.J, Vance, D, Shoemaker, C, Mantis, N. 登録日 2015-09-29 公開日 2016-08-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.032 Å) 主引用文献 Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit. Proteins, 84, 2016
7D3M	FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY R50 分子名称: O/TIBET/99 VP1, O/TIBET/99 VP2, O/TIBET/99 VP3, ... 著者 He, Y, Lou, Z. 登録日 2020-09-19 公開日 2021-04-14 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (3.94 Å) 主引用文献 Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization. Plos Pathog., 17, 2021
7D3K	FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY B77 分子名称: B77 VH, B77 VL, O/TIBET/99 VP1, ... 著者 He, Y, Lou, Z. 登録日 2020-09-19 公開日 2021-04-14 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization. Plos Pathog., 17, 2021
8F0I	Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody COVA309-22 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA309-22 heavy chain, COVA309-22 light chain, ... 著者 Yuan, M, Wilson, I.A. 登録日 2022-11-03 公開日 2023-09-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Broad SARS-CoV-2 neutralization by monoclonal and bispecific antibodies derived from a Gamma-infected individual. Iscience, 26, 2023
7MEP	BG505 SOSIP.v5.2(7S) in complex with the monoclonal antibodies Rh.33172 mAb.1 and RM19R 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2(7S) - gp120, ... 著者 Antanasijevic, A, Ward, A.B. 登録日 2021-04-07 公開日 2022-01-26 最終更新日 2022-08-10 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
7M30	Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25 分子名称: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain, 1-32 Fab Heavy Chain, ... 著者 Wrapp, D, McLellan, J.S. 登録日 2021-03-17 公開日 2021-08-11 最終更新日 2022-03-23 実験手法 ELECTRON MICROSCOPY (3.81 Å) 主引用文献 Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8, 2022
4HFW	Anti Rotavirus Antibody 分子名称: 6-26 Fab Heavy chain, 6-26 Fab Light chain, SULFATE ION 著者 Spiller, B.W, Aiyegbo, M, Crowe, J.E. 登録日 2012-10-05 公開日 2013-05-29 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore. Plos One, 8, 2013
7LM8	Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with two cross-neutralizing antibodies CV38-142 and COVA1-16 Fabs isolated from COVID-19 patients 分子名称: 1,2-ETHANEDIOL, COVA1-16 Fab heavy chain, COVA1-16 Fab light chain, ... 著者 Liu, H, Wilson, I.A. 登録日 2021-02-05 公開日 2021-03-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.936 Å) 主引用文献 A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Cell Host Microbe, 29, 2021
8CZ8	Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics 分子名称: Mesothelin, cleaved form, SULFATE ION, ... 著者 Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E. 登録日 2022-05-24 公開日 2023-06-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics Front. Drug Discov., 3, 2023
8SGU	Crystal structure of the SARS-CoV-2 receptor binding domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Sankhala, R.S, Jensen, J.L, Joyce, M.G. 登録日 2023-04-13 公開日 2023-12-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Antibody targeting of conserved sites of vulnerability on the SARS-CoV-2 spike receptor-binding domain. Structure, 32, 2024
6CDI	Cryo-EM structure at 3.6 A resolution of vaccine-elicited antibody vFP16.02 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ... 著者 Acharya, P, Xu, K, Liu, K, Carragher, B, Potter, C.S, Kwong, P.D. 登録日 2018-02-08 公開日 2018-05-16 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nat. Med., 24, 2018

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