PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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4J2R	Middle domain of influenza A virus RNA-dependent polymerase PB2 分子名称: Polymerase basic protein 2 著者 Qiu, H, Tsurumura, T, Tsumori, Y, Hatakeyama, D, Kuzuhara, T, Tsuge, H. 登録日 2013-02-05 公開日 2014-02-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Crystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virus ACTA CRYSTALLOGR.,SECT.F, 70, 2014
5EF9	Structure of Influenza B Lee PB2 cap-binding domain 分子名称: Polymerase basic protein 2 著者 Ma, X, Shia, S. 登録日 2015-10-23 公開日 2015-11-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Molecular Basis of mRNA Cap Recognition by Influenza B Polymerase PB2 Subunit. J.Biol.Chem., 291, 2016
3T5J	Ternary complex of HNE Adduct modified DNA (5'-TXG-3' vs 13-mer) with Dpo4 and incoming dDTP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*TP*(HN1)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... 著者 Banerjee, S, Christov, P.P, Kozekova, A, Rizzo, C.J, Stone, M.P. 登録日 2011-07-27 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chem.Res.Toxicol., 25, 2012
3T5K	Ternary complex of HNE Adduct modified DNA (5'-TXG-3' vs 14-mer) with Dpo4 and incoming dDTP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*TP*(HN0)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... 著者 Banerjee, S, Christov, P.P, Kozekova, A, Rizzo, C.J, Stone, M.P. 登録日 2011-07-27 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chem.Res.Toxicol., 25, 2012
3T5L	Ternary complex of HNE Adduct modified DNA (5'-CXG-3' vs 14-mer) with Dpo4 and incoming dDGT 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*CP*(HN0)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... 著者 Banerjee, S, Christov, P.P, Kozekova, A, Rizzo, C.J, Stone, M.P. 登録日 2011-07-27 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chem.Res.Toxicol., 25, 2012
3T5H	Ternary complex of HNE Adduct modified DNA (5'-CXG-3' vs 13-mer) with Dpo4 and incoming dDGT 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*CP*(HN1)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... 著者 Banerjee, S, Christov, P.P, Kozekova, A, Rizzo, C.J, Stone, M.P. 登録日 2011-07-27 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chem.Res.Toxicol., 25, 2012
7LYG	Zika virus RNA promoter stem-loop A with tRNA-scaffold 分子名称: RNA promoter stem-loop A fused with tRNA 著者 Lee, E.H, Choi, K.H. 登録日 2021-03-06 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.804 Å) 主引用文献 Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase. Nat Commun, 12, 2021
6N4O	Human Argonaute2-miR-122 bound to a seed and supplementary paired target 分子名称: Protein argonaute-2, RNA (5'-R(*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3') 著者 Sheu-Gruttadauria, J, MacRae, I.J. 登録日 2018-11-19 公開日 2019-05-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.899 Å) 主引用文献 Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2. Embo J., 38, 2019
5IZH	Lassa virus L protein cap-snatching endonuclease. apo form 分子名称: RNA-directed RNA polymerase L 著者 Reguera, J, Cusack, S. 登録日 2016-03-25 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog., 12, 2016
4WBZ	tRNA-processing enzyme (apo form 2) 分子名称: Poly A polymerase 著者 Yamashita, S, Tomtia, K. 登録日 2014-09-04 公開日 2015-04-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015
2W9A	Ternary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA with incoming dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*DOC)-3', 5'-D(*TP*CP*AP*CP*O2GP*GP*AP*AP*TP*CP *CP*TP*TP*CP*CP*CP*CP*C)-3', ... 著者 Eoff, R.L, Zhang, H, Kosekov, I.D, Rizzo, C.J, Egli, M, Guengerich, F.P. 登録日 2009-01-22 公開日 2009-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-Function Relationships in Miscoding by Sulfolobus Solfataricus DNA Polymerase Dpo4: Guanine N2,N2-Dimethyl Substitution Produces Inactive and Miscoding Polymerase Complexes. J.Biol.Chem., 284, 2009
2W9C	Ternary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA with incoming dTTP 分子名称: 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*DOCP)-3', 5'-D(*TP*CP*AP*CP*O2GP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', DNA POLYMERASE IV, ... 著者 Eoff, R.L, Zhang, H, Kosekov, I.D, Rizzo, C.J, Egli, M, Guengerich, F.P. 登録日 2009-01-22 公開日 2009-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-Function Relationships in Miscoding by Sulfolobus Solfataricus DNA Polymerase Dpo4: Guanine N2,N2-Dimethyl Substitution Produces Inactive and Miscoding Polymerase Complexes. J.Biol.Chem., 284, 2009
7Q2J	Quaternary Complex of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC Homer 分子名称: Elongin-B, Elongin-C, N-[5-[4-[[5-[[(2S)-3,3-dimethyl-1-[(2S,4R)-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-5-oxidanylidene-pentyl]carbamoyl]phenyl]-2-(4-methylpiperazin-1-yl)phenyl]-6-oxidanylidene-4-(trifluoromethyl)-1H-pyridine-3-carboxamide, ... 著者 Kraemer, A, Doelle, A, Schwalm, M.P, Adhikari, B, Wolf, E, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2021-10-25 公開日 2021-11-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization. Cell Chem Biol, 30, 2023
8AS6	Structure of the SFTSV L protein bound to 5' cRNA hook [5' HOOK] 分子名称: RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*C)-3'), RNA-dependent RNA-polymerase L protein 著者 Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. 登録日 2022-08-18 公開日 2023-01-18 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
5EWG	Ternary complex of human DNA polymerase eta inserting rATP opposite an 8-Oxodeoxyguanosine Lesion 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Su, Y, Egli, M, Guengerich, F.P. 登録日 2015-11-20 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
5EWF	Ternary complex of human DNA polymerase eta inserting rCTP opposite an 8-Oxodeoxyguanosine Lesion 分子名称: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Su, Y, Egli, M, Guengerich, F.P. 登録日 2015-11-20 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.782 Å) 主引用文献 Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
5EWE	Ternary complex of human DNA polymerase eta inserting rCTP opposite template G 分子名称: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Su, Y, Egli, M, Guengerich, F.P. 登録日 2015-11-20 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
3H4D	Ternary complex of human DNA polymerase iota with template U/T and incoming dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC)), 5'-D(*TP*(BRU)P*GP*GP*GP*TP*CP*CP*T), ... 著者 Jain, R, Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. 登録日 2009-04-18 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Replication across template T/U by human DNA polymerase-iota. Structure, 17, 2009
3H4B	Ternary complex of human DNA polymerase iota with template U/T and incoming dATP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(BRU)P*GP*GP*GP*TP*CP*CP*T)-3', ... 著者 Jain, R, Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. 登録日 2009-04-18 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Replication across template T/U by human DNA polymerase-iota. Structure, 17, 2009
3ISD	Ternary complex of human DNA polymerase beta with an abasic site (THF): DAPCPP mismatch 分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, 5'-D(*CP*CP*GP*AP*CP*(3DR)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ... 著者 Beard, W.A, Shock, D.D, Batra, V.K, Pedersen, L.C, Wilson, S.H. 登録日 2009-08-25 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". J.Biol.Chem., 284, 2009
7KI3	Human Argonaute2:miR-122 bound to the HCV genotype 1a site-1 RNA 分子名称: BARIUM ION, HCV genotype 1a miR-122 site-1, Protein argonaute-2, ... 著者 Gebert, L.F.R, MacRae, I.J. 登録日 2020-10-22 公開日 2021-10-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A structured RNA motif locks Argonaute2:miR-122 onto the 5' end of the HCV genome. Nat Commun, 12, 2021
4JWM	Ternary complex of D256E mutant of DNA Polymerase Beta 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Perera, L, Ping, L, Shock, D.D, Beard, W.A, Pedersen, L.C, Pedersen, L.G, Wilson, S.H. 登録日 2013-03-27 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Amino Acid Substitution in the Active Site of DNA Polymerase beta Explains the Energy Barrier of the Nucleotidyl Transfer Reaction. J.Am.Chem.Soc., 135, 2013
3WI0	P453H/I471T mutant of PB2 middle domain from influenza virus A/Puerto Rico/8/34(H1N1) 分子名称: Polymerase basic protein 2 著者 Tsurumura, T, Yoshida, T, Tsuge, H. 登録日 2013-09-04 公開日 2013-12-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Conformational Polymorphism of m7GTP in Crystal Structure of the PB2 Middle Domain from Human Influenza A Virus Plos One, 8, 2013
4L1P	Crystal Structure of Human Rtf1 Plus3 domain 分子名称: GLYCEROL, RNA polymerase-associated protein RTF1 homolog 著者 Wier, A.D, Heroux, A, VanDemark, A.P. 登録日 2013-06-03 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proc.Natl.Acad.Sci.USA, 110, 2013
4L1U	Crystal Structure of Human Rtf1 Plus3 Domain in Complex with Spt5 CTR Phosphopeptide 分子名称: GLYCEROL, RNA polymerase-associated protein RTF1 homolog, SULFATE ION, ... 著者 Wier, A.D, Heroux, A, VanDemark, A.P. 登録日 2013-06-03 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.424 Å) 主引用文献 Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proc.Natl.Acad.Sci.USA, 110, 2013

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