3T5J

Ternary complex of HNE Adduct modified DNA (5'-TXG-3' vs 13-mer) with Dpo4 and incoming dDTP

Summary for 3T5J

• Entry DOI: 10.2210/pdb3t5j/pdb
• Related: 3T5H 3T5K 3T5L
• Descriptor: DNA polymerase IV, DNA (5'-D(*CP*AP*TP*(HN1)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... (6 entities in total)
• Functional Keywords: ternary complex of dpo4-dna-datp, dna polymerase, hne, dna-transferase complex, dna/transferase
• Biological source: Sulfolobus solfataricus P2; More
• Cellular location: Cytoplasm (Probable): Q97W02
• Total number of polymer chains: 3
• Total formula weight: 48967.13

Authors

Banerjee, S.,Christov, P.P.,Kozekova, A.,Rizzo, C.J.,Stone, M.P. (deposition date: 2011-07-27, release date: 2012-02-15, Last modification date: 2024-02-28)

• Primary citation: Banerjee, S.,Christov, P.P.,Kozekova, A.,Rizzo, C.J.,Egli, M.,Stone, M.P.; Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV.; Chem.Res.Toxicol., 25:422-435, 2012; PubMed: 22313351; DOI: 10.1021/tx200460j

Experimental method

X-RAY DIFFRACTION (2.4 Å)