3H4D

Ternary complex of human DNA polymerase iota with template U/T and incoming dGTP

Summary for 3H4D

• Entry DOI: 10.2210/pdb3h4d/pdb
• Related: 3H40 3H4B
• Descriptor: DNA polymerase iota, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC)), 5'-D(*TP*(BRU)P*GP*GP*GP*TP*CP*CP*T), ... (6 entities in total)
• Functional Keywords: dna polymerase iota, replication, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, nucleus, schiff base, transferase, replication-dna complex, replication/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q9UNA4
• Total number of polymer chains: 3
• Total formula weight: 49486.92

Authors

Jain, R.,Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2009-04-18, release date: 2009-07-21, Last modification date: 2023-09-06)

• Primary citation: Jain, R.,Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K.; Replication across template T/U by human DNA polymerase-iota.; Structure, 17:974-980, 2009; PubMed: 19604477; DOI: 10.1016/j.str.2009.04.011

Experimental method

X-RAY DIFFRACTION (2.2 Å)