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3RUX
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Crystal structure of biotin-protein ligase BirA from Mycobacterium tuberculosis in complex with an acylsulfamide bisubstrate inhibitor
分子名称: 5'-deoxy-5'-[({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}sulfamoyl)amino]adenosine, BirA bifunctional protein
著者Geders, T.W, Finzel, B.C.
登録日2011-05-05
公開日2011-12-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis.
Chem.Biol., 18, 2011
1UNJ
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Crystal structure of a 7-Aminoactinomycin D complex with non-complementary DNA
分子名称: 5'-D(*TP*TP*AP*GP*BRU*TP)-3', 7-AMINO-ACTINOMYCIN D
著者Alexopoulos, E.C, Klement, R, Jares-Erijman, E.A, Uson, I, Jovin, T.M, Sheldrick, G.M.
登録日2003-09-10
公開日2004-12-16
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal and Solution Structures of 7-Amino-Actinomycin D Complexes with D(Ttagbrut), D(Ttagtt) and D(Tttagttt)
Acta Crystallogr.,Sect.D, 61, 2005
3TA6
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Structure of Mycobacterium tuberculosis triosephosphate isomerase
分子名称: CITRATE ANION, Triosephosphate isomerase
著者Connor, S.E, Capodagli, G.C, Deaton, M.K, Pegan, S.D.
登録日2011-08-03
公開日2011-11-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structural and functional characterization of Mycobacterium tuberculosis triosephosphate isomerase.
Acta Crystallogr.,Sect.D, 67, 2011
3V1U
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Crystal structure of a beta-ketoacyl reductase FabG4 from Mycobacterium tuberculosis H37Rv complexed with NAD+ and Hexanoyl-CoA at 2.5 Angstrom resolution
分子名称: (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-PENTAMETHYL-4,7,10,13,16,19-HEXAOXADOCOSANE-2,21-DIOL, 3-oxoacyl-(Acyl-carrier-protein) reductase, HEXANOYL-COENZYME A, ...
著者Dutta, D, Bhattacharyya, S, Das, A.K.
登録日2011-12-10
公開日2012-11-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of hexanoyl-CoA bound to beta-ketoacyl reductase FabG4 of Mycobacterium tuberculosis
Biochem.J., 450, 2013
3QQS
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Anthranilate phosphoribosyltransferase (TRPD) from Mycobacterium tuberculosis (complex with inhibitor ACS172)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2,2'-iminodibenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-02-16
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
3R0J
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Structure of PhoP from Mycobacterium tuberculosis
分子名称: POSSIBLE TWO COMPONENT SYSTEM RESPONSE TRANSCRIPTIONAL POSITIVE REGULATOR PHOP, R-1,2-PROPANEDIOL, SULFATE ION
著者Menon, S, Wang, S.
登録日2011-03-08
公開日2011-07-13
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Response Regulator PhoP from Mycobacterium tuberculosis Reveals a Dimer through the Receiver Domain.
Biochemistry, 50, 2011
3R88
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Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS145)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-amino-4,5-dimethoxybenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S.
登録日2011-03-23
公開日2012-09-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
3R6C
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Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS179)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 8-methoxyphenanthro[3,4-d][1,3]dioxole-5,6-dicarboxylic acid, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-03-21
公開日2012-09-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
3UN7
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Crystal structure of PBPA from MYCOBACTERIUM TUBERCULOSIS
分子名称: Penicillin-binding protein A
著者Fedarovich, A, Davies, C.
登録日2011-11-15
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The role of the beta5-alpha11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis
J.Mol.Biol., 418, 2012
3QR9
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Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (apo structure)
分子名称: Anthranilate phosphoribosyltransferase, GLYCEROL
著者Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-02-17
公開日2011-06-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
3QS8
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Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS174)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-benzylbenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-02-20
公開日2012-08-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
3UU1
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Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS142)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-amino-3,5-dimethylbenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S.
登録日2011-11-27
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
3UID
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Crystal Structure of Protein Ms6760 from Mycobacterium smegmatis
分子名称: Putative uncharacterized protein
著者Bajaj, R.A, Miallau, L, Cascio, D, Arbing, M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2011-11-04
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.571 Å)
主引用文献Crystal structure of the toxin Msmeg_6760, the structural homolog of Mycobacterium tuberculosis Rv2035, a novel type II toxin involved in the hypoxic response.
Acta Crystallogr F Struct Biol Commun, 72, 2016
2Z2P
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Crystal Structure of catalytically inactive H270A virginiamycin B lyase from Staphylococcus aureus with Quinupristin
分子名称: 5-(2-DIETHYLAMINO-ETHANESULFONYL)-21-HYDROXY-10-ISOPROPYL-11,19-DIMETHYL-9,26-DIOXA-3,15,28-TRIAZA-TRICYCLO[23.2.1.00,255]OCTACOSA-1(27),12,17,19,25(28)-PENTAENE-2,8,14,23-TETRAONE, MAGNESIUM ION, Quinupristin, ...
著者Korczynska, M, Berghuis, A.M.
登録日2007-05-25
公開日2007-06-19
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Streptogramin B Resistance in Staphylococcus Aureus by Virginiamycin B Lyase
Proc.Natl.Acad.Sci.USA, 104, 2007
5HV8
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Solution structure of an octanoyl- loaded acyl carrier protein domain from module MLSA2 of the mycolactone polyketide synthase.
分子名称: S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate, Type I modular polyketide synthase
著者Vance, S, Tkachenko, O, Thomas, B, Bassuni, M, Hong, H, Nietlispach, D, Broadhurst, R.W.
登録日2016-01-28
公開日2016-03-09
最終更新日2019-10-23
実験手法SOLUTION NMR
主引用文献Sticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthase.
Biochem.J., 473, 2016
2Y08
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Structure of the substrate-free FAD-dependent tirandamycin oxidase TamL
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Carlson, J.C, Li, S, Gunatilleke, S.S, Anzai, Y, Burr, D.A, Podust, L.M, Sherman, D.H.
登録日2010-11-30
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes
Nat.Chem, 3, 2011
1USL
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Structure Of Mycobacterium tuberculosis Ribose-5-Phosphate Isomerase, RpiB, Rv2465c, Complexed With Phosphate.
分子名称: PHOSPHATE ION, RIBOSE 5-PHOSPHATE ISOMERASE B
著者Roos, A.K, Andersson, C.E, Unge, T, Jones, T.A, Mowbray, S.L.
登録日2003-11-25
公開日2004-01-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Mycobacterium Tuberculosis Ribose-5-Phosphate Isomerase Has a Known Fold, But a Novel Active Site
J.Mol.Biol., 335, 2004
5Z9Y
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Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP
分子名称: 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Thiazole synthase
著者Zhang, J, Zhang, B, Zhao, Y, Yang, X, Huang, M, Cui, P, Zhang, W, Li, J, Zhang, Y.
登録日2018-02-05
公開日2018-04-11
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG).
Biochem. Biophys. Res. Commun., 497, 2018
6A7V
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Crystal structure of Mycobacterium tuberculosis VapBC11 toxin-antitoxin complex
分子名称: Antitoxin VapB11, PENTAETHYLENE GLYCOL, Ribonuclease VapC11, ...
著者Deep, A, Thakur, K.G.
登録日2018-07-04
公開日2018-10-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin-antitoxin system: targeting a tRNase to tackle mycobacterial adaptation.
Nucleic Acids Res., 46, 2018
3ULB
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Crystal structure of the pleckstrin homology domain of Saccharomyces cerevisiae Avo1, a TORC2 subunit, in the P212121 crystal form
分子名称: Target of rapamycin complex 2 subunit AVO1
著者Pan, D, Matsuura, Y.
登録日2011-11-10
公開日2012-04-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the pleckstrin homology domain of Saccharomyces cerevisiae Avo1 and its human orthologue Sin1, an essential subunit of TOR complex 2
Acta Crystallogr.,Sect.F, 68, 2012
3ULC
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Crystal structure of the pleckstrin homology domain of Saccharomyces cerevisiae Avo1, a TORC2 subunit, in the P3121 crystal form
分子名称: Target of rapamycin complex 2 subunit AVO1
著者Pan, D, Matsuura, Y.
登録日2011-11-10
公開日2012-04-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the pleckstrin homology domain of Saccharomyces cerevisiae Avo1 and its human orthologue Sin1, an essential subunit of TOR complex 2
Acta Crystallogr.,Sect.F, 68, 2012
7L6C
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Crystal Structure of Enoyl-[acyl-carrier-protein] reductase InhA from Mycobacterium abscessus in complex with NAD
分子名称: 1,2-ETHANEDIOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-12-23
公開日2021-01-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Efficacy and Mode of Action of a Direct Inhibitor of Mycobacterium abscessus InhA.
Acs Infect Dis., 8, 2022
6BS3
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Crystal structure of ADP-bound bacterial Get3-like A and B in Mycobacterium tuberculosis
分子名称: ADENOSINE-5'-DIPHOSPHATE, Anion transporter, CALCIUM ION, ...
著者Li, H, Hu, K, Kovach, A.
登録日2017-12-01
公開日2019-05-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterization of Guided Entry of Tail-Anchored Proteins 3 Homologues in Mycobacterium tuberculosis.
J.Bacteriol., 201, 2019
6BS5
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Crystal structure of AMP-PNP-bound bacterial Get3-like A and B in Mycobacterium tuberculosis
分子名称: Anion transporter, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Li, H, Hu, K, Kovach, A.
登録日2017-12-01
公開日2019-05-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Characterization of Guided Entry of Tail-Anchored Proteins 3 Homologues in Mycobacterium tuberculosis.
J.Bacteriol., 201, 2019
6BS4
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Crystal structure of ATPgammaS-bound bacterial Get3-like A and B in Mycobacterium tuberculosis
分子名称: ADENOSINE-5'-DIPHOSPHATE, Anion transporter, MAGNESIUM ION, ...
著者Li, H, Hu, K, Kovach, A.
登録日2017-12-01
公開日2019-05-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Characterization of Guided Entry of Tail-Anchored Proteins 3 Homologues in Mycobacterium tuberculosis.
J.Bacteriol., 201, 2019

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