2Z2P
Crystal Structure of catalytically inactive H270A virginiamycin B lyase from Staphylococcus aureus with Quinupristin
Summary for 2Z2P
| Entry DOI | 10.2210/pdb2z2p/pdb |
| Related | 1SM1 |
| Related PRD ID | PRD_000505 |
| Descriptor | Virginiamycin B lyase, Quinupristin, MAGNESIUM ION, ... (4 entities in total) |
| Functional Keywords | quinupristin, dalfopristin, streptogramin, synercid, lyase-antibiotic complex, antibiotic resistance, antibiotic, virginiamycin b lyase, virginiamycin b hydrolase, lyase/antibiotic |
| Biological source | Staphylococcus aureus More |
| Total number of polymer chains | 4 |
| Total formula weight | 69595.87 |
| Authors | Korczynska, M.,Berghuis, A.M. (deposition date: 2007-05-25, release date: 2007-06-19, Last modification date: 2023-11-15) |
| Primary citation | Korczynska, M.,Mukhtar, T.A.,Wright, G.D.,Berghuis, A.M. Structural Basis for Streptogramin B Resistance in Staphylococcus Aureus by Virginiamycin B Lyase Proc.Natl.Acad.Sci.USA, 104:10388-, 2007 Cited by PubMed: 17563376DOI: 10.1073/PNAS.0701809104 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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