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8U4V
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Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-1, and Nanobody
分子名称: Anti-fab nanobody, COP-1 sFab Heavy Chain, COP-1 sFab Light Chain, ...
著者Vecchio, A.J.
登録日2023-09-11
公開日2023-10-25
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment
Commun Biol, 7, 2024
8U4U
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Crystal structure of 53BP1 tandem Tudor domain homodimer engineered with two disulfide bridges
分子名称: TP53-binding protein 1
著者Cui, G, Botuyan, M.V, Thompson, J.R, Mer, G.
登録日2023-09-11
公開日2023-09-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.79 Å)
主引用文献An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Nat Commun, 14, 2023
8U4T
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Structure of tetrameric CXCR4 in complex with REGN7663 Fab
分子名称: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, C-X-C chemokine receptor type 4, CHOLESTEROL, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4S
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Structure of trimeric CXCR4 in complex with REGN7663 Fab
分子名称: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, C-X-C chemokine receptor type 4, CHOLESTEROL, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4R
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Structure of REGN7663-Fab bound CXCR4
分子名称: C-X-C chemokine receptor type 4, CHOLESTEROL, REGN7663 Fab heavy chain, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4Q
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Structure of REGN7663 Fab-bound CXCR4/Gi complex
分子名称: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4P
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Structure of AMD3100-bound CXCR4/Gi complex
分子名称: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4O
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Structure of CXCL12-bound CXCR4/Gi complex
分子名称: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4N
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Structure of Apo CXCR4/Gi complex
分子名称: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4L
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Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ...
著者Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N.
登録日2023-09-10
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain
To Be Published
8U4K
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Structure of the HER2/HER4/BTC Heterodimer Extracellular Domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betacellulin, ...
著者Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N.
登録日2023-09-10
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (4.27 Å)
主引用文献Structure of the HER2/HER4/BTC Heterodimer Extracellular Domain
To Be Published
8U4J
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Structure of the HER4/BTC Homodimer Extracellular Domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betacellulin, ...
著者Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N.
登録日2023-09-10
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the HER4/BTC Homodimer Extracellular Domain
To Be Published
8U4I
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BU of 8u4i by Molmil
Structure of the HER4/NRG1b Homodimer Extracellular Domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ...
著者Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N.
登録日2023-09-10
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain
To Be Published
8U4F
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Crystal Structure of BlCel9A from Glycoside Hydrolase Family 9 in Complex with Cellohexaose
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
著者Araujo, E.A, Polikarpov, I.
登録日2023-09-10
公開日2024-02-14
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Molecular mechanism of cellulose depolymerization by the two-domain BlCel9A enzyme from the glycoside hydrolase family 9.
Carbohydr Polym, 329, 2024
8U4E
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Cryo-EM structure of long form insulin receptor (IR-B) with three IGF2 bound, asymmetric conformation.
分子名称: Insulin receptor, Insulin-like growth factor II
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2023-09-10
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8U4D
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TRPV1 in nanodisc bound with PI-Br4, consensus structure
分子名称: (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1
著者Arnold, W.R, Julius, D, Cheng, Y.
登録日2023-09-10
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
8U4C
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Cryo-EM structure of long form insulin receptor (IR-B) with four IGF2 bound, symmetric conformation.
分子名称: Insulin receptor, Insulin-like growth factor II
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2023-09-10
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8U4B
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BU of 8u4b by Molmil
Cryo-EM structure of long form insulin receptor (IR-B) in the apo state
分子名称: Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2023-09-10
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8U4A
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Crystal Structure of BlCel9A from Glycoside Hydrolase Family 9 in Complex with Cellotriose
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
著者Araujo, E.A, Polikarpov, I.
登録日2023-09-10
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Molecular mechanism of cellulose depolymerization by the two-domain BlCel9A enzyme from the glycoside hydrolase family 9.
Carbohydr Polym, 329, 2024
8U49
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The Apo Crystal Structure of BlCel9A from Glycoside Hydrolase Family 9
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
著者Araujo, E.A, Polikarpov, I.
登録日2023-09-10
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular mechanism of cellulose depolymerization by the two-domain BlCel9A enzyme from the glycoside hydrolase family 9.
Carbohydr Polym, 329, 2024
8U48
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Crystal structure of Bacteroides thetaiotamicron BT1285 D161A-E163A inactive Endoglycosidase in complex with high-mannose N-glycan (Man9GlcNAc2) substrate
分子名称: Endo-beta-N-acetylglucosaminidase, PHOSPHATE ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Sastre, D.E, Sultana, N, Navarro, M.V.A.S, Sundberg, E.J.
登録日2023-09-09
公開日2024-05-29
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate.
Nat Commun, 15, 2024
8U47
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Crystal structure of Bacteroides thetaiotaomicron VPI-5482 Endoglycosidase BT1285
分子名称: Endo-beta-N-acetylglucosaminidase, MAGNESIUM ION, PHOSPHATE ION
著者Sastre, D.E, Sultana, N, Sundberg, E.J.
登録日2023-09-09
公開日2024-05-29
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate.
Nat Commun, 15, 2024
8U46
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Crystal structure of Bacteroides thetaiotaomicron VPI-5482 Endoglycosidase BT1285 D161A-E163A inactive version
分子名称: Endo-beta-N-acetylglucosaminidase
著者Sastre, D.E, Sultana, N, Sundberg, E.J.
登録日2023-09-09
公開日2024-05-29
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate.
Nat Commun, 15, 2024
8U45
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Crystal Structure Analysis of Aspergillus fumigatus alkaline protease
分子名称: Alkaline protease 1, CALCIUM ION, CHLORIDE ION, ...
著者Fernandez, D, Diec, D.D.L, Guo, W, Russi, S.
登録日2023-09-08
公開日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision.
Sci Rep, 13, 2023
8U44
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CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06
分子名称: 05.GC.w2.3C10-H1_SI06 Heavy chain, 05.GC.w2.3C10-H1_SI06 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Moore, N, Han, J, Ward, A.B, Wilson, I.A.
登録日2023-09-08
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Persistence of germinal center B cell responses after influenza virus vaccination in humans
To Be Published

221716

件を2024-06-26に公開中

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