8U4V
Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-1, and Nanobody
Summary for 8U4V
Entry DOI | 10.2210/pdb8u4v/pdb |
EMDB information | 41897 41899 41915 |
Descriptor | Claudin-4, Heat-labile enterotoxin B chain, COP-1 sFab Light Chain, ... (7 entities in total) |
Functional Keywords | claudin, fab, toxin, nanobody, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 102162.35 |
Authors | Vecchio, A.J. (deposition date: 2023-09-11, release date: 2023-10-25, Last modification date: 2024-07-03) |
Primary citation | Erramilli, S.K.,Dominik, P.K.,Ogbu, C.P.,Kossiakoff, A.A.,Vecchio, A.J. Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Commun Biol, 7:733-733, 2024 Cited by PubMed: 38886509DOI: 10.1038/s42003-024-06437-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.99 Å) |
Structure validation
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