8U4V

Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-1, and Nanobody

Summary for 8U4V

• Entry DOI: 10.2210/pdb8u4v/pdb
• EMDB information: 41897 41899 41915
• Descriptor: Claudin-4, Heat-labile enterotoxin B chain, COP-1 sFab Light Chain, ... (7 entities in total)
• Functional Keywords: claudin, fab, toxin, nanobody, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 102162.35

Authors

Vecchio, A.J. (deposition date: 2023-09-11, release date: 2023-10-25, Last modification date: 2023-12-13)

• Primary citation: Vecchio, A.J.; Cryo-EM structures of a synthetic antibody against 22 kDa claudin-4 reveal its complex with Clostridium perfringens enterotoxin; To be published,

Experimental method

ELECTRON MICROSCOPY (2.99 Å)