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3F6O
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BU of 3f6o by Molmil
Crystal structure of ArsR family transcriptional regulator, RHA00566
分子名称: BROMIDE ION, Probable transcriptional regulator, ArsR family protein
著者Dong, A, Xu, X, Zheng, H, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-11-06
公開日2008-11-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of ArsR family transcriptional regulator, RHA00566
To be Published
8XRP
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BU of 8xrp by Molmil
The Cryo-EM structure of IL-12, receptor subunit beta-1 and receptor subunit beta-2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, Interleukin-12 receptor subunit beta-2, ...
著者Chen, H.Q, Wang, X.Q, Ge, X.F, Zeng, J.W, Wang, J.W.
登録日2024-01-07
公開日2024-07-24
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structure and assembly of the human IL-12 signaling complex.
Structure, 2024
8WMS
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BU of 8wms by Molmil
Crystal structure of human DPPA3 in complex with human UHRF1 PHD domain
分子名称: Developmental pluripotency-associated protein 3, E3 ubiquitin-protein ligase UHRF1, ZINC ION
著者Shiraishi, N, Arita, K.
登録日2023-10-04
公開日2024-07-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of human DPPA3 in complex with human UHRF1 PHD domain
To Be Published
5EDU
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BU of 5edu by Molmil
Crystal structure of human histone deacetylase 6 catalytic domain 2 in complex with trichostatin A
分子名称: Maltose-binding periplasmic protein, Histone deacetylase 6 chimera, POTASSIUM ION, ...
著者Hai, Y, Christianson, D.W.
登録日2015-10-22
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
6OPI
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BU of 6opi by Molmil
phosphorylated ERK2 with SCH-CPD336
分子名称: (3R)-N-[3-(2-cyclopropylpyridin-4-yl)-1H-indazol-5-yl]-3-(methoxymethyl)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}ethyl)pyrrolidine-3-carboxamide, Mitogen-activated protein kinase 1
著者Vigers, G.P, Smith, D.
登録日2019-04-25
公開日2019-07-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2.
Proc.Natl.Acad.Sci.USA, 116, 2019
5EKY
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BU of 5eky by Molmil
Crystal structure of deoxyribose-phosphate aldolase from Escherichia coli (K58E-Y96W mutant)
分子名称: 1,3-BUTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Deoxyribose-phosphate aldolase
著者Classen, T, Dick, M, Pietruszka, J, Weiergraeber, O.H.
登録日2015-11-04
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies.
Chem Sci, 7, 2016
8XTG
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BU of 8xtg by Molmil
Crystal structure of methyltransferase MpaG' in complex with SAH and DMMPA
分子名称: O-desmethyl mycophenolic acid, O-methyltransferase mpaG', S-ADENOSYL-L-HOMOCYSTEINE
著者You, C, Pan, Y.J, Li, S.Y, Feng, Y.G.
登録日2024-01-10
公開日2024-08-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for substrate flexibility of the O-methyltransferase MpaG' involved in mycophenolic acid biosynthesis.
Protein Sci., 33, 2024
8XTF
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BU of 8xtf by Molmil
Crystal structure of methyltransferase MpaG' in complex with SAH and FDHMP-3C
分子名称: 4-farnesyl-3,5-dihydroxy-6-methylphthalide-3C, O-methyltransferase mpaG', S-ADENOSYL-L-HOMOCYSTEINE
著者You, C, Pan, Y.J, Li, S.Y, Feng, Y.G.
登録日2024-01-10
公開日2024-08-28
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural basis for substrate flexibility of the O-methyltransferase MpaG' involved in mycophenolic acid biosynthesis.
Protein Sci., 33, 2024
5EGC
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BU of 5egc by Molmil
Structure of the Adeno-Associated Virus Serotype 1 sialic acid complex
分子名称: Capsid protein, MAGNESIUM ION, N-acetyl-alpha-neuraminic acid
著者Huang, L.Y, Agbandje-McKenna, M.
登録日2015-10-27
公開日2016-03-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.011 Å)
主引用文献Characterization of the Adeno-Associated Virus 1 and 6 Sialic Acid Binding Site.
J.Virol., 90, 2016
5EPZ
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BU of 5epz by Molmil
Human Angiogenin in complex with sulphate anions at a basic solution
分子名称: Angiogenin, GLYCEROL, SULFATE ION
著者Chatzileontiadou, D.S.M, Leonidas, D.D.
登録日2015-11-12
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The ammonium sulfate inhibition of human angiogenin.
Febs Lett., 590, 2016
8XTE
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BU of 8xte by Molmil
Crystal structure of methyltransferase MpaG' in complex with SAH and FDHMP
分子名称: 4-farnesyl-3,5-dihydroxy-6-methylphthalide, O-methyltransferase mpaG', S-ADENOSYL-L-HOMOCYSTEINE
著者You, C, Pan, Y.J, Li, S.Y, Feng, Y.G.
登録日2024-01-10
公開日2024-08-28
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural basis for substrate flexibility of the O-methyltransferase MpaG' involved in mycophenolic acid biosynthesis.
Protein Sci., 33, 2024
5W0W
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BU of 5w0w by Molmil
Crystal structure of Protein Phosphatase 2A bound to TIPRL
分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ...
著者Wu, C, Zheng, A, Li, J, Satyshur, K, Xing, Y.
登録日2017-06-01
公開日2018-01-17
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Methylation-regulated decommissioning of multimeric PP2A complexes.
Nat Commun, 8, 2017
5W6V
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BU of 5w6v by Molmil
The Structure of human Argonaute-1 in complex with the hook motif of human GW182
分子名称: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*AP*A)-3'), Trinucleotide repeat-containing gene 6A protein
著者Elkayam, E, Faehnle, C.R, Joshua-Tor, L.
登録日2017-06-17
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.828 Å)
主引用文献Multivalent Recruitment of Human Argonaute by GW182.
Mol. Cell, 67, 2017
5EQO
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BU of 5eqo by Molmil
Human Angiogenin in complex with sulphate anions at an acidic solution
分子名称: Angiogenin, SULFATE ION
著者Chatzileontiadou, D.S.M, Leonidas, D.D.
登録日2015-11-13
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The ammonium sulfate inhibition of human angiogenin.
Febs Lett., 590, 2016
5EQW
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BU of 5eqw by Molmil
Structure of the major structural protein D135 of Acidianus tailed spindle virus (ATSV)
分子名称: NITRATE ION, Putative major coat protein
著者Hochstein, R.A, Lintner, N.G, Young, M.J, Lawrence, C.M.
登録日2015-11-13
公開日2016-11-16
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (1.679 Å)
主引用文献Structural studies ofAcidianustailed spindle virus reveal a structural paradigm used in the assembly of spindle-shaped viruses.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W63
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BU of 5w63 by Molmil
Crystal structure of channel catfish BAX
分子名称: 1,2-ETHANEDIOL, Apoptosis regulator bax, SULFATE ION
著者Robin, A.Y, Colman, P.M, Czabotar, P.E, Luo, C.S.
登録日2017-06-16
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.436 Å)
主引用文献Ensemble Properties of Bax Determine Its Function.
Structure, 26, 2018
5VGZ
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BU of 5vgz by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-12
公開日2017-08-23
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
8YA8
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BU of 8ya8 by Molmil
The crystal structure of human Rtel1 HHD2 domain
分子名称: Regulator of telomere elongation helicase 1
著者Chun, I.S, Kim, M.S.
登録日2024-02-08
公開日2024-02-28
最終更新日2024-09-11
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of the HHD2 domain in human RTEL1
Biodesign, 12, 2024
6OPH
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BU of 6oph by Molmil
phosphorylated ERK2 with GDC-0994
分子名称: 1-[(1~{S})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one, Mitogen-activated protein kinase 1
著者Vigers, G.P, Smith, D.
登録日2019-04-25
公開日2019-07-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2.
Proc.Natl.Acad.Sci.USA, 116, 2019
8YBE
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BU of 8ybe by Molmil
Cryo-EM structure of Maltose Binding Protein
分子名称: Maltose/maltodextrin-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Yoo, Y, Park, K, Kim, H.
登録日2024-02-13
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Atomic resolution structure of MBP using Cryo-EM
To Be Published
5EMU
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BU of 5emu by Molmil
Crystal structure of deoxyribose-phosphate aldolase from Escherichia coli (K58E-Y96W mutant) after acetaldehyde treatment and heating
分子名称: 1-BUTANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Deoxyribose-phosphate aldolase
著者Weiergraeber, O.H, Dick, M, Pietruszka, J.
登録日2015-11-06
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies.
Chem Sci, 7, 2016
5WKP
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BU of 5wkp by Molmil
Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and Iron-Sulfur Cluster Scaffold Protein ISCU1, and E. coli ACP1 protein at 3.15A
分子名称: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
著者Boniecki, M.T, Cygler, M.
登録日2017-07-25
公開日2017-11-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
4XP3
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BU of 4xp3 by Molmil
Crystal structure of ERK2 in complex with an inhibitor
分子名称: 2-amino-1,9-dihydro-6H-purine-6-thione, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ...
著者Gelin, M, Allemand, F, Labesse, G, Guichou, J.F.
登録日2015-01-16
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.782 Å)
主引用文献Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography.
Acta Crystallogr.,Sect.D, 71, 2015
5EOP
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BU of 5eop by Molmil
Crystal structure of human Angiogenin at 1.35 Angstroms resolution
分子名称: Angiogenin
著者Chatzileontiadou, D.S.M, Tsirkone, V.G, Dossi, K, Leonidas, D.D.
登録日2015-11-10
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The ammonium sulfate inhibition of human angiogenin.
Febs Lett., 590, 2016
5WVI
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BU of 5wvi by Molmil
The resting state of yeast proteasome
分子名称: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
著者Ding, Z, Cong, Y.
登録日2016-12-25
公開日2017-03-22
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx
Cell Res., 27, 2017

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件を2024-09-11に公開中

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