5EMU

Crystal structure of deoxyribose-phosphate aldolase from Escherichia coli (K58E-Y96W mutant) after acetaldehyde treatment and heating

Summary for 5EMU

• Entry DOI: 10.2210/pdb5emu/pdb
• Related: 5eky 5el1
• Descriptor: Deoxyribose-phosphate aldolase, 1-BUTANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• Functional Keywords: dera, tim barrel, lyase, suicide inhibitor
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 1
• Total formula weight: 28933.08

Authors

Weiergraeber, O.H.,Dick, M.,Pietruszka, J. (deposition date: 2015-11-06, release date: 2016-05-04, Last modification date: 2024-01-10)

• Primary citation: Dick, M.,Hartmann, R.,Weiergraber, O.H.,Bisterfeld, C.,Classen, T.,Schwarten, M.,Neudecker, P.,Willbold, D.,Pietruszka, J.; Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies.; Chem Sci, 7:4492-4502, 2016; PubMed: 30155096; DOI: 10.1039/c5sc04574f

Experimental method