5EL1
Crystal structure of deoxyribose-phosphate aldolase from Escherichia coli (K58E-Y96W mutant) after acetaldehyde treatment
Summary for 5EL1
| Entry DOI | 10.2210/pdb5el1/pdb |
| Related | 5eky 5emu |
| Descriptor | Deoxyribose-phosphate aldolase, 1-BUTANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
| Functional Keywords | dera, tim barrel, lyase, suicide inhibitor |
| Biological source | Escherichia coli K-12 |
| Total number of polymer chains | 1 |
| Total formula weight | 28933.08 |
| Authors | Weiergraeber, O.H.,Dick, M.,Pietruszka, J. (deposition date: 2015-11-04, release date: 2016-05-04, Last modification date: 2024-01-10) |
| Primary citation | Dick, M.,Hartmann, R.,Weiergraber, O.H.,Bisterfeld, C.,Classen, T.,Schwarten, M.,Neudecker, P.,Willbold, D.,Pietruszka, J. Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies. Chem Sci, 7:4492-4502, 2016 Cited by PubMed: 30155096DOI: 10.1039/c5sc04574f PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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