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8DXS
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Cryo-EM structure of RBD-directed neutralizing antibody P2B4 in complex with prefusion SARS-CoV-2 spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, P2B4 Heavy chain, P2B4 Light chain, ...
著者Reddem, E.R, Shapiro, L.
登録日2022-08-03
公開日2022-12-07
最終更新日2023-01-18
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2.
Emerg Microbes Infect, 12, 2023
7S5Q
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BU of 7s5q by Molmil
Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibodies CS44 and COVA1-16
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 Heavy chain, ...
著者Yuan, M, Wilson, I.A.
登録日2021-09-11
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7S5R
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BU of 7s5r by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibodies CV07-287 and COVA1-16
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 Heavy chain, ...
著者Yuan, M, Wilson, I.A.
登録日2021-09-11
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7M3I
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BU of 7m3i by Molmil
Structure of SARS-CoV-2 spike protein receptor binding domain in complex with a neutralizing antibody, CV2-75 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV2-75 Fab Heavy chain, CV2-75 Fab Light chain, ...
著者Hurlburt, N.K, Pancera, M.
登録日2021-03-18
公開日2021-05-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects.
Cell Rep, 36, 2021
7TQS
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BU of 7tqs by Molmil
Coxsackievirus A21 capsid subdomain in complex with mouse polyclonal antibody pAbC-3
分子名称: MYRISTIC ACID, VP1, VP2, ...
著者Antanasijevic, A, Ward, A.B.
登録日2022-01-26
公開日2023-01-04
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献High-resolution structural analysis of enterovirus-reactive polyclonal antibodies in complex with whole virions.
Pnas Nexus, 1, 2022
7RFB
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BU of 7rfb by Molmil
Crystal structure of broadly neutralizing antibody mAb1198 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Flyak, A.I, Bjorkman, P.J.
登録日2021-07-14
公開日2022-01-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.
Immunity, 55, 2022
7RFC
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Crystal structure of broadly neutralizing antibody mAb1382 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Flyak, A.I, Bjorkman, P.J.
登録日2021-07-14
公開日2022-01-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.
Immunity, 55, 2022
7S0D
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BU of 7s0d by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-014
分子名称: N-612-014 Fab Heavy Chain, N-612-014 Light Chain, Spike glycoprotein
著者Barnes, C.O, Bjorkman, P.J.
登録日2021-08-30
公開日2021-10-06
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
7S0E
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BU of 7s0e by Molmil
Structure of the SARS-CoV-2 S1 subunit in complex with antibody N-612-004
分子名称: N-612-004 Fab heavy chain, N-612-004 Light Chain, Spike glycoprotein
著者Barnes, C.O, Bjorkman, P.J.
登録日2021-08-30
公開日2021-10-06
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
7S0B
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BU of 7s0b by Molmil
Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody N-612-056
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-612-056 Fab Heavy Chain, N-612-056 Light Chain, ...
著者Tanaka, S, Barnes, C.O, Bjorkman, P.J.
登録日2021-08-30
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
7S0C
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BU of 7s0c by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-017
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-612-017 Fab Heavy Chain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2021-08-30
公開日2021-10-06
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
7N6P
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BU of 7n6p by Molmil
Crystal structure of the anti-EBOV and SUDV monoclonal antibody 1C3 Fab
分子名称: 1C3 Fab heavy chain, 1C3 Fab light chain
著者Milligan, J.C, Yu, X, Buck, T, Saphire, E.O.
登録日2021-06-08
公開日2022-04-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses.
Cell, 185, 2022
7K9Z
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BU of 7k9z by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with the Fab fragments of neutralizing antibodies 298 and 52
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 298 Fab Heavy Chain, 298 Fab Light Chain, ...
著者Newton, J.C, Kucharska, I, Rujas, E, Cui, H, Julien, J.P.
登録日2020-09-29
公開日2020-10-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers.
Nat Commun, 12, 2021
8H73
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BU of 8h73 by Molmil
Crystal structure of antibody scFv against M2e Influenza peptide
分子名称: CITRATE ANION, Single Chain Variable Fragment
著者Kumar, U, Madni, Z.K, Gaur, V, Salunke, D.M.
登録日2022-10-18
公開日2023-08-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献A structure and knowledge-based combinatorial approach to engineering universal scFv antibodies against influenza M2 protein.
J.Biomed.Sci., 30, 2023
8H3B
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BU of 8h3b by Molmil
Crystal structure of antibody scFv against M2e Influenza peptide
分子名称: GLYCEROL, Single Chain Variable Fragment
著者Kumar, U, Madni, Z.K, Gaur, V, Salunke, D.M.
登録日2022-10-08
公開日2023-08-02
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A structure and knowledge-based combinatorial approach to engineering universal scFv antibodies against influenza M2 protein.
J.Biomed.Sci., 30, 2023
8H3C
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BU of 8h3c by Molmil
Crystal structure of M2e Influenza peptide in complex with antibody scFv
分子名称: Matrix protein 2, Single Chain Variable Fragment
著者Kumar, U, Madni, Z.K, Gaur, V, Salunke, D.M.
登録日2022-10-08
公開日2023-08-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.43 Å)
主引用文献A structure and knowledge-based combinatorial approach to engineering universal scFv antibodies against influenza M2 protein.
J.Biomed.Sci., 30, 2023
3GJE
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BU of 3gje by Molmil
Rational development of high-affinity T-cell receptor-like antibodies
分子名称: Fab Heavy Chain, Fab Light Chain
著者Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E, Kleber, S, Stenner-Liewen, F, Bauer, S, McMichael, A, Knuth, A, Abken, H, Hombach, A.A, Cerundolo, V, Jones, E.Y, Renner, C.
登録日2009-03-08
公開日2009-04-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
7N07
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BU of 7n07 by Molmil
Crystal structure of the apo 3D6 antibody fragment
分子名称: Fab 3D6 heavy chain, Fab 3D6 light chain, SULFATE ION
著者Cook, J.D, Lee, J.E.
登録日2021-05-25
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies.
Commun Biol, 5, 2022
7N04
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BU of 7n04 by Molmil
Crystal structure of the apo F240 antibody fragment
分子名称: Fab F240 heavy chain, Fab F240 light chain, alpha-D-glucopyranose
著者Cook, J.D, Lee, J.E.
登録日2021-05-25
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.70000517 Å)
主引用文献Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies.
Commun Biol, 5, 2022
7N08
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BU of 7n08 by Molmil
Crystal structure of the 3D6 antibody fragment bound to the HIV-1 gp41 immunodominant region
分子名称: Fab 3D6 heavy chain, Fab 3D6 light chain, HIV-1 gp41 immunodominant region
著者Cook, J.D, Lee, J.E.
登録日2021-05-25
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies.
Commun Biol, 5, 2022
7N05
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BU of 7n05 by Molmil
Crystal structure of the F240 antibody fragment bound to the HIV-1 gp41 immunodominant region
分子名称: ACETATE ION, Fab F240 heavy chain, Fab F240 light chain, ...
著者Cook, J.D, Lee, J.E.
登録日2021-05-25
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies.
Commun Biol, 5, 2022
8TOO
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BU of 8too by Molmil
Crystal structure of Epstein-Barr virus gp42 in complex with antibody 4C12
分子名称: 4C12 heavy chain, 4C12 light chain, Glycoprotein 42
著者Bu, W, Kumar, A, Board, N, Kim, J, Dowdell, K, Zhang, S, Lei, Y, Hostal, A, Krogmann, T, Wang, Y, Pittaluga, S, Marcotrigiano, J, Cohen, J.I.
登録日2023-08-03
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells.
Immunity, 57, 2024
8TNN
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BU of 8tnn by Molmil
Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with gp42 antibody A10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, A10 heavy chain, A10 light chain, ...
著者Bu, W, Kumar, A, Board, N, Kim, J, Dowdell, K, Zhang, S, Lei, Y, Hostal, A, Krogmann, T, Wang, Y, Pittaluga, S, Marcotrigiano, J, Cohen, J.I.
登録日2023-08-02
公開日2024-03-27
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells.
Immunity, 57, 2024
7V0N
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BU of 7v0n by Molmil
Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-21
分子名称: IgG 21 Fab heavy chain, IgG 21 Fab light chain, Spike glycoprotein E1, ...
著者Bandyopadhyay, A, Klose, T, Kuhn, R.J.
登録日2022-05-10
公開日2023-04-05
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 120, 2023
7V0O
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BU of 7v0o by Molmil
Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-94
分子名称: IgG 94 Fab heavy chain, IgG 94 Fab light chain, Spike glycoprotein E1, ...
著者Bandyopadhyay, A, Klose, T, Kuhn, R.J.
登録日2022-05-10
公開日2023-04-05
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 120, 2023

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