8TOO

Crystal structure of Epstein-Barr virus gp42 in complex with antibody 4C12

Summary for 8TOO

Entry DOI	10.2210/pdb8too/pdb
Descriptor	4C12 light chain, 4C12 heavy chain, Glycoprotein 42, ... (4 entities in total)
Functional Keywords	viral protein, antibody, immune system
Biological source	Mus musculus (mouse) More
Total number of polymer chains	12
Total formula weight	258816.99
Authors	Bu, W.,Kumar, A.,Board, N.,Kim, J.,Dowdell, K.,Zhang, S.,Lei, Y.,Hostal, A.,Krogmann, T.,Wang, Y.,Pittaluga, S.,Marcotrigiano, J.,Cohen, J.I. (deposition date: 2023-08-03, release date: 2024-03-27)
Primary citation	Bu, W.,Kumar, A.,Board, N.L.,Kim, J.,Dowdell, K.,Zhang, S.,Lei, Y.,Hostal, A.,Krogmann, T.,Wang, Y.,Pittaluga, S.,Marcotrigiano, J.,Cohen, J.I. Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells. Immunity, 57:559-573.e6, 2024 Cited by PubMed: 38479361 DOI: 10.1016/j.immuni.2024.02.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation