7V0N
Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-21
Summary for 7V0N
Entry DOI | 10.2210/pdb7v0n/pdb |
EMDB information | 26945 |
Descriptor | Spike glycoprotein E1, IgG 21 Fab heavy chain, IgG 21 Fab light chain, ... (4 entities in total) |
Functional Keywords | cryo-em, single particle, virus neutralization, inter virion crosslink, aggregation, virus-immune system complex, virus/immune system |
Biological source | Eastern equine encephalitis virus More |
Total number of polymer chains | 16 |
Total formula weight | 481478.90 |
Authors | Bandyopadhyay, A.,Klose, T.,Kuhn, R.J. (deposition date: 2022-05-10, release date: 2023-04-05, Last modification date: 2024-02-21) |
Primary citation | Williamson, L.E.,Bandyopadhyay, A.,Bailey, K.,Sirohi, D.,Klose, T.,Julander, J.G.,Kuhn, R.J.,Crowe Jr., J.E. Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 120:e2213690120-e2213690120, 2023 Cited by PubMed: 36961925DOI: 10.1073/pnas.2213690120 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (5.9 Å) |
Structure validation
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