8G2Z
 
 | | 48-nm doublet microtubule from Tetrahymena thermophila strain CU428 | | 分子名称: | B2B3_fMIP, B5B6_fMIP, CFAM166A, ... | | 著者 | Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. | | 登録日 | 2023-02-06 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins.
Nat Commun, 14, 2023
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7PJZ
 | | Structure of the 70S-EF-G-GDP ribosome complex with tRNAs in chimeric state 2 (CHI2-EF-G-GDP) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | | 登録日 | 2021-08-24 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Structural mechanism of GTPase-powered ribosome-tRNA movement.
Nat Commun, 12, 2021
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8BB3
 | | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with PEG linker (conformation #1) | | 分子名称: | 1,2-ETHANEDIOL, Elongin-B, Elongin-C, ... | | 著者 | Kraemer, A, Doelle, A, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2022-10-12 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with PEG linker (conformation #1)
To Be Published
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8BEM
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8BB2
 | | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with PEG linker (conformation #2) | | 分子名称: | 1,2-ETHANEDIOL, Elongin-B, Elongin-C, ... | | 著者 | Kraemer, A, Doelle, A, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2022-10-12 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with PEG linker (conformation #2)
To Be Published
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8GHT
 | | Cryo-electron microscopy structure of the zinc transporter from Bordetella bronchiseptica | | 分子名称: | CADMIUM ION, PHOSPHATIDYLETHANOLAMINE, Putative membrane protein | | 著者 | Liu, Q, Chai, J, Pang, C.X, Shanklin, J. | | 登録日 | 2023-03-12 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structural mechanism of intracellular autoregulation of zinc uptake in ZIP transporters.
Nat Commun, 14, 2023
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7PPO
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7PJS
 | | Structure of the 70S ribosome with tRNAs in the classical pre-translocation state and apramycin (C) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | | 登録日 | 2021-08-24 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.35 Å) | | 主引用文献 | Structural mechanism of GTPase-powered ribosome-tRNA movement
Nat Commun, 12, 2021
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8G4M
 | | Vaccine-elicited human antibody 2C06 in complex with HIV-1 envelope trimer BG505 DS-SOSIP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | 著者 | Wang, S, Morano, N.C, Shapiro, L, Kwong, P.D. | | 登録日 | 2023-02-10 | | 公開日 | 2023-07-12 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.
Cell Rep, 42, 2023
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8G4T
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8FFZ
 | | TFIIIA-TFIIIC-Brf1-TBP complex bound to 5S rRNA gene | | 分子名称: | DNA (151-MER), Transcription factor IIIA, Transcription factor IIIB 70 kDa subunit,TATA-box-binding protein, ... | | 著者 | Talyzina, A, He, Y. | | 登録日 | 2022-12-11 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation.
Mol.Cell, 83, 2023
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8FDU
 | | Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi (local refined on AAA3-AAA5 and LIS1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, Platelet-activating factor acetylhydrolase IB subunit beta,Platelet-activating factor acetylhydrolase IB subunit beta,human LIS1 protein with a SNAP tag | | 著者 | Ton, W, Wang, Y, Chai, P. | | 登録日 | 2022-12-04 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport.
Nat.Struct.Mol.Biol., 30, 2023
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7ZHC
 | | Moss spermine/spermidine acetyl transferase (PpSSAT) in complex with AcetylCoA and polyethylen glycol | | 分子名称: | ACETYL COENZYME *A, GLYCEROL, N-acetyltransferase domain-containing protein, ... | | 著者 | Morera, S, Kopecny, D, Vigouroux, A. | | 登録日 | 2022-04-06 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.819 Å) | | 主引用文献 | Biochemical and structural basis of polyamine, lysine and ornithine acetylation catalyzed by spermine/spermidine N-acetyl transferase in moss and maize.
Plant J., 114, 2023
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8FCY
 | | Engineered human dynein motor domain in microtubule-bound state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase | | 著者 | Ton, W, Wang, Y, Chai, P. | | 登録日 | 2022-12-01 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport.
Nat.Struct.Mol.Biol., 30, 2023
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8BB5
 | | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with Aryl linker | | 分子名称: | 1,2-ETHANEDIOL, Elongin-B, Elongin-C, ... | | 著者 | Kraemer, A, Doelle, A, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2022-10-12 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization.
Cell Chem Biol, 30, 2023
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7RMI
 | | SP6-11 biased agonist bound to active human neurokinin 1 receptor in complex with miniGs/q70 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A. | | 登録日 | 2021-07-27 | | 公開日 | 2021-11-03 | | 最終更新日 | 2022-01-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Nat.Chem.Biol., 18, 2022
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7RMG
 | | Substance P bound to active human neurokinin 1 receptor in complex with miniGs/q70 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A. | | 登録日 | 2021-07-27 | | 公開日 | 2021-11-03 | | 最終更新日 | 2022-01-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Nat.Chem.Biol., 18, 2022
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7RMH
 | | Substance P bound to active human neurokinin 1 receptor in complex with miniGs399 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A. | | 登録日 | 2021-07-27 | | 公開日 | 2021-11-03 | | 最終更新日 | 2022-01-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Nat.Chem.Biol., 18, 2022
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8B8B
 | | Multimerization domain of Munia virus 1 phosphoprotein | | 分子名称: | Munia Bornavirus 1 phosphoprotein, NITRATE ION | | 著者 | Chenavier, F, Tarbouriech, N, Bourhis, J.M, Tomonaga, K, Horie, M, Crepin, T. | | 登録日 | 2022-10-04 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing.
Viruses, 14, 2022
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7Q65
 | | Cryo-em structure of the Nup98 fibril polymorph 2 | | 分子名称: | Nuclear pore complex protein Nup98 | | 著者 | Ibanez de Opakua, A, Geraets, J.A, Frieg, B, Dienemann, C, Savastano, A, Rankovic, M, Cima-Omori, M.-S, Schroeder, G.F, Zweckstetter, M. | | 登録日 | 2021-11-05 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Molecular interactions of FG nucleoporin repeats at high resolution.
Nat.Chem., 14, 2022
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8FZQ
 | | Dehosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | | 著者 | Levring, J, Terry, D.S, Kilic, Z, Fitzgerald, G.A, Blanchard, S.C, Chen, J. | | 登録日 | 2023-01-29 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | CFTR function, pathology and pharmacology at single-molecule resolution.
Nature, 616, 2023
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7QVI
 | | Fiber-forming RubisCO derived from ancestral sequence reconstruction and rational engineering | | 分子名称: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, RubisCO large subunit | | 著者 | Schulz, L, Zarzycki, J, Prinz, S, Schuller, J.M, Erb, T.J, Hochberg, G.K.A. | | 登録日 | 2022-01-21 | | 公開日 | 2022-10-12 | | 最終更新日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Evolution of increased complexity and specificity at the dawn of form I Rubiscos.
Science, 378, 2022
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8BCJ
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7Q67
 | | Cryo-em structure of the Nup98 fibril polymorph 4 | | 分子名称: | Nuclear pore complex protein Nup98 | | 著者 | Ibanez de Opakua, A, Geraets, J.A, Frieg, B, Dienemann, C, Savastano, A, Rankovic, M, Cima-Omori, M.-S, Schroeder, G.F, Zweckstetter, M. | | 登録日 | 2021-11-05 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Molecular interactions of FG nucleoporin repeats at high resolution.
Nat.Chem., 14, 2022
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7QVP
 | | Human collided disome (di-ribosome) stalled on XBP1 mRNA | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Denk, T.G, Tesina, P, Beckmann, R. | | 登録日 | 2022-01-22 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
Nat Commun, 13, 2022
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